Discipline: Genome Engineering
70 Results for 'Genome Engineering'
- Technologies (4)
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Technologies 4
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Gene Drives
Since the 1940s, researchers have thought of using gene drives to eradicate populations of pests and disease vectors, and to reduce or eliminate invasive species that wreak havoc on natural ecosystems. The idea of a gene drive stems from nature itself, where in sexually reproducing organisms a certain version of a gene is preferentially passed... -
AAV-Engineering For Advanced Gene Therapy
Gene therapy with AAV (adeno-associated virus) as a delivery vehicle is a leading therapeutic modality for genetic disorders that is approved in Europe for the metabolic disease Familial Lipoprotein Lipase Deficiency. It is currently being tested in clinical trials in the U.S. to treat other rare conditions like the retinal Leber Congenital Amaurosis and the... -
High Density Information Storage in DNA
A new method developed at the Wyss Institute allows for synthesis of oligonucleotides by the thousands on a single DNA microchip — a collection of thousands of different DNA segments attached to a glass slide or other solid surface. Until now, generating long strands of DNA has been challenging and labor-intensive. Yet Wyss researchers have... -
Multiplex Automated Genomic Engineering (MAGE)
Developed at the Wyss Institute, MAGE harnesses the natural principles of evolution to do all the heavy lifting of genome design and automates these steps to dramatically shorten the time scale required to produce microbes with specialized functionalities for manufacturing, sensing and therapeutic applications. Genome engineering has a wide range of applications, from developing new...
News 52
Multimedia 14
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Video/AnimationCRISPR-Cas: Molecular RecordingIn this video, Wyss Institute and Harvard Medical School researchers George Church and Seth Shipman explain how they engineered a new CRISPR system-based technology that enables the chronological recording of digital information, like that representing still and moving images, in living bacteria. Credit: Wyss Institute at Harvard University -
Video/AnimationWyss Study: Memory GenesResearchers at the Wyss Institute and the Personal Genome Project (PGP) are using Lumosity games to evaluate memory functions and response times. The genomes of high performers will be sequenced, with the goal of uncovering the relationship between genetics, memory, attention, and reaction speed. This video featuring George Church, Core Faculty of the Wyss Institute and Professor... -
Audio/PodcastFireside Chat with George ChurchAudio recording of a fireside chat with Wyss Core Faculty member George Church at the 2016 Convergence Forum, held in Chatham, Mass. on May 12 and 13, 2016. Moderated by Alison Taunton-Rigby. -
Audio/PodcastGeorge Church: Responsibility, art & science of intentional extinction, de-extinction & agingGeorge Church Responsibility, art & science of intentional extinction, de-extinction & aging Wednesday, Feb 17, 2016 ArtScience @ Le Lab Lecture Series: Art, Design, Engineering & Biology – Core Faculty from the Wyss Institute for Biologically Inspired Engineering at Harvard University discuss how the arts and design are informing the frontiers of science. ArtScience @... -
Audio/PodcastMusings on Science and Society, with a dash of CRISPRThe Science Soapbox team sits down with Dr. George Church to talk everything from the dawn of CRISPR to the place of science fiction in society. Dr. Church is Professor of Genetics at Harvard Medical School, leader of the Synthetic Biology Platform at the Wyss institute, and director of PersonalGenomes.org. This episode was recorded on... -
Video/AnimationDistributed Cell Division CounterGenetically engineered E. coli containing a fluorescing red protein enabled a Wyss Institute and Harvard Medical School team to analyze the population fluctuations of gut microbes by comparing proportion of “marked” to “unmarked” cells. Credit: Wyss Institute at Harvard University