Focus Area: Synthetic Biology
275 Results for 'Synthetic Biology'
- Technologies (30)
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- News (192)
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Technologies 30
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GC Therapeutics: Changing the Future of Cell Therapies
GC Therapeutics (GCTx) is applying their stem cell-engineering TFome platform to overcome barriers in the development and manufacturing of cell therapies to improve patient access across a broad range of disease areas. -
Instrument-Free Molecular Diagnostics
A synthetic biology-based molecular diagnostics platform that enables the creation of low-cost, highly accurate tests for non-clinical settings. -
AminoX: Making Better Protein Drugs, Quicker and Cheaper
AminoX enables protein drugs to only become active in the tumor microenvironment and not elsewhere in the body to avoid immune-related adverse effects in the body. By designing and building non-standard amino acids into strategic positions of protein drugs, AminoX provides tumor-specific, and longer-lasting target inhibition. -
Ichor: Reversing Aging
Ichor is addressing multiple age-related diseases by identifying genetic interventions that reprogram old cells to a younger state. Therapies based on these interventions could improve survival for cancer patients and long-term cardiovascular and neurological health. -
Paper-Based Diagnostics
With the imminent threat of new pandemics and frequent disease outbreaks exemplified by the recent Ebola and Zika epidemics, there is a growing need for low-cost, easily deployable and simple-to-use diagnostic tools. The Wyss Institute has developed paper-based synthetic gene networks as a next generation diagnostic technology for use in global healthcare crises and patient... -
DNA Nanostructures for Drug Delivery
Researchers at the Wyss Institute have developed two methods for building arbitrarily shaped nanostructures using DNA, with a focus on translating the technology towards nanofabrication and drug delivery applications. One proprietary nanofabrication technique, called “DNA-brick self-assembly,” uses short, synthetic strands of DNA that work like interlocking Lego® bricks. It capitalizes on the ability to program...
News 192
Multimedia 53
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Video/AnimationFinding a Balance In Bipolar Disorder Through Drug Prediction and Organoid-Based Drug ScreeningCircaVent is a high-throughput drug screening platform that combines predictive algorithms, preclinical models, and human brain organoids to efficiently identify and test drugs that could treat the underlying causes of bipolar disorder. CircaVent is initially focused on addressing the circadian rhythm disruptions that are a common hallmark of BD, and could dramatically speed up the... -
Video/AnimationHuman Skin Rejuvenation: Li Li, Ph.D.In this episode of Conquer Aging or Die Trying, host Michael Lustgarten, Ph.D. speaks to Wyss Postdoctoral Fellow Li Li, Ph.D. about the technology she’s developing for skin rejuvenation. -
Video/Animation20-ish Questions with George Church20-ish Questions shows a different side of Wyss Institute faculty, touching on aspects of their personal life, hobbies, interests, as well as their research. This round follows George Church, a founding Core Faculty member of the Wyss Institute and lead of the Synthetic Biology Focus Area. Credit: Wyss Institute at Harvard University -
Video/AnimationThe Dish Live with special guest George ChurchIn this very special live taping of “The Dish,” host Johannes Fruehauf sits down with renowned geneticist and Wyss Core Faculty member, George Church, Ph.D. Widely known for discovering the first direct genomic sequencing method, Church has reshaped the world of genetics. A professor at Harvard and MIT and a founding professor at the Wyss... -
Audio/PodcastSeqVerify: A New Easily Accessible Tool for Comprehensive Cell Line Quality Assessment – The Stem Cell ReportDuring the last decade, advances in genome editing and pluripotent stem cell (PSC) culture have let researchers generate edited PSC lines to study a wide variety of biological questions. However, abnormalities in cell lines such as aneuploidy, mutations, on-target and off-target editing errors, and microbial contamination can arise during PSC culture or due to undesired... -
Video/AnimationAminoX: Making Better Protein Drugs, Quicker and CheaperA synthetic biology and advanced chemistry platform that efficiently incorporates non-standard amino acids by hacking the ubiquitous protein synthesis process. Credit: Wyss Institute at Harvard University