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Technologies 4

• Bone Marrow-Like Scaffolds for Accelerating Immune Reconstitution
  Bone marrow transplants containing hematopoietic stem cells from an immune-compatible (“allogeneic”) donor can cure patients with otherwise fatal blood disorders including multiple myeloma and leukemias by reconstituting their entire immune systems after chemotherapy. However, following such a “hematopoietic stem cell transplantation” (HSCT), the restoration of T cell immunity – which depends on the production of...
• Single-Cell Encapsulation for Improved Cell Therapies
  Mesenchymal stromal cells (MSCs) are valued for their ability to secrete compounds that modulate the body’s immune system, making them an attractive solution for existing problems with cell therapies including host-vs-graft disease and organ transplant rejections. However, MSCs are rapidly cleared from the body and can come under fire from the immune system. Efforts to...
• DNA Data Storage
  The genetic material DNA has garnered considerable interest as a medium for digital information storage because its density and durability are superior to those of existing silicon-based storage media. For example, DNA is at least 1000-fold more dense than the most compact solid-state hard drive and at least 300-fold more durable than the most stable...
• Biomaterial Scaffolds for T Cell Expansion
  Immunotherapy, or tweaking the body’s own immune system to treat disease, is attracting significant attention in the medical field for its potential to offer long-lasting cures with fewer side effects than chemotherapy or other drugs. One type of immunotherapy involves isolating T cells (a type of white blood cell) from a patient’s body, sometimes modifying...

News 19

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• Video/​Animation
  
  Tough yet flexible treatment for babies in the womb
  November 30, 2020
• Press Release
  
  A viable vaccine for tough tumors
  November 10, 2020
• Press Release
  
  Direct control of dendritic cells for tracking and immune modulation
  May 18, 2020

Events 1

• Oct 26, 2016,
  1:00pm - 2:00pm
  Wyss Event
  
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  Self-Improving Microvascular Materials
  The unique structures and functions of biological materials arise from the unique processes of patterning and rearrangement they employ – namely morphogenesis.  Esser-Kahn seeks to mimic the structures formed by biological systems by mimicking the process which forms them.  He will detail his initial efforts to develop a simple synthetic morphogenetic system that repatterns microvascular... Free and open to public

Multimedia 2

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  Video/Animation
  Light-driven fine chemical production in yeast biohybrids
  Wyss Institute Core Faculty member Neel Joshi explains the concept of yeast biohybrids and how they can be used to harvest energy from light to drive the production of fine chemicals. Credit: Wyss Institute at Harvard University

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  Audio/Podcast
  Slug Slime Inspires Scientists To Invent Sticky Surgical Glue
  Slug Slime Inspires Scientists To Invent Sticky Surgical Glue was originally broadcast on NPR’s All Things Considered on July 27, 2017. This story features Wyss Institute Technology Development Fellow Jianyu Li. The original broadcast story can be found here.