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Technologies 4

• Engineered Live Biotherapeutic Product (eLBP) to Protect the Microbiome from Antibiotics
  eLBP is a safe and cost-effective therapeutic for patients treated with beta-lactam antibiotics that safeguards against the loss of health-essential microbes while preventing the development and spread of antibiotic resistance.
• SomaCode: Getting Cell Therapies Where They Need to Go
  SomaCode is solving the problem of cell therapy delivery by identifying unique molecular “zip codes” for disease and engineering cells to home to those zip codes, making cell therapies safer and more effective.
• Circe: Tailored Fats for Food Applications
  A fermentation-based platform that uses greenhouses gases to produce food-grade fats without the use of plants or animals. The Wyss Institute is de-risking this technology and is seeking strategic partnerships with companies and individuals who are interested in assisting with its development and commercialization.
• Circe: Transforming Greenhouse Gases into Biodegradable Products
  Circe is a platform technology that uses engineered microbes to produce valuable, biodegradable synthetic polymers from greenhouse gases, minimizing the environmental impact of manufacturing. Potential applications include biodegradable plastics and packaging, energy-efficient agriculture, clean personal care products, and more. Circe is a platform technology that uses engineered microbes to produce valuable, biodegradable synthetic polymers from greenhouse gases, minimizing the environmental impact of manufacturing. Potential applications include biodegradable plastics and packaging, energy-efficient agriculture, clean personal care products, and more.

Collaborations 1

• Brain Targeting Program
  Pre-competitive multi-partner industry collaboration that aims to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain.

News 21

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• Press Release
  
  Enhanced cancer immunotherapies through cytokine-labeled T cells
  January 10, 2023
• Press Release
  
  DNA nanostructures grow up to become micron-scale megastructures
  December 21, 2022
• Translation News
  
  Wyss Institute at Harvard University partners with Northpond Labs to launch RNA solutions company EnPlusOne Biosciences
  December 19, 2022

Events 1

• Nov 17 → 18, 2016
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  Advances in Cell Engineering, Imaging, and Screening
  VIB’s Tools and Technologies meetings provide a forum for top academic speakers and scientists from both established and emerging companies to present their latest scientific achievements and exciting technological solutions. The first edition of Advances in Cell Engineering, Imaging and Screening will bring together some of the most highly regarded Academics and Companies in the...

Multimedia 6

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  Video/Animation
  Seed-dependent crisscross DNA-origami slats
  This animation explains how the newly invented crisscross origami method can be used to build functionalized micron-scale DNA megastructures composed of many unique DNA origami “slats,” each with their own complexity and interactive properties. Credit: Wyss Institute at Harvard University

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  Video/Animation
  SomaCode: GPS for Cell Therapy
  Just like zip codes help drivers navigate to specific addresses using a GPS system, the molecular ‘zip codes’ identified via the SomaCode platform can be used to deliver cell therapies to their specific targets in the human body, increasing the therapies’ efficacy and reducing side effects. Credit: Wyss Institute at Harvard University

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  Video/Animation
  eToehold: an RNA-detecting control element for use in RNA therapeutics, diagnostics and cell therapies
  This animation shows an example of an eToehold that detects and signals the presence of a specific viral RNA in a human cell. After the virus has injected its RNA into a host cell, the RNA acts as a “trigger RNA” by binding to a complementary sequence within the eToehold specifically engineered for its detection....

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  Video/Animation
  Circe: Using Microbes to Make Biodegradable Products
  Current manufacturing methods release harmful greenhouse gases and pollution, and many of the products produced do not biodegrade, damaging our ecosystems even further. What if we could turn greenhouse gases into biodegradable products? Researchers at the Wyss Institute are using synthetic biology to make this a reality. Credit: Wyss Institute at Harvard University

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  Video/Animation
  Self-regenerating bacterial hydrogels as intestinal wound patches
  This animation explains how self-regenerating bacterial hydrogels could be used as adhesive patches to help intestinal wounds heal. Credit: Wyss Institute at Harvard University.

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  Video/Animation
  New Wyss Institute Initiative – 3D Organ Engineering
  Wyss Institute Core Faculty members Christopher Chen and Jennifer Lewis describe the Wyss Institute’s new initiative focused on organ engineering, which leverages our expertise in biomaterials, tissue engineering, three dimensional biofabrication, and stem cell development.