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Technologies 1

• NanoRx: Mechanically-Activated Drug Targeting
  The Wyss team has developed a novel drug targeting nanotechnology that is activated locally by mechanical forces, either endogenous high shear stresses in blood created by vascular occlusion or mechanical energy applied locally using low-energy ultrasound radiation. Today, vascular blockage is the leading cause of death and disability in United States and Europe. Current therapies...

News 5

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• Press Release
  
  Platelet “Decoys” Outsmart Both Clots and Cancer
  February 13, 2019
• Translation News
  
  Predicting side effects before they happen
  May 1, 2018
• Press Release
  
  Pulmonary Thrombosis-on-a-Chip provides new avenue for drug development
  May 22, 2017

Multimedia 2

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  Video/Animation
  NanoRx: Clot-Busting Nanotherapeutic
  In this animation, learn how the Wyss Institute clot-busting nanotherapeutic is activated by fluid high shear force – which occurs where blood flows through vessels narrowed by obstruction – to specifically target clots and dissolve them away. By pairing this drug with an intra-arterial device that restores blood flow to complete obstructions, the drug-device combination...

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  Video/Animation
  Clot-busting nanotherapeutic
  Wyss Core Faculty member Donald E. Ingber describes the clot-busting nanotherapeutic. Credit: Wyss Institute at Harvard University