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Technologies 1

• Athlete-Derived Probiotics
  Elite athletes possess extraordinary physical abilities enabling them to reach peak performances and recover quickly. The question is, can we extract information from their biology and use it to boost the performance level and speed up recovery of every-day-athletes? Research in different laboratories over the past years has discovered potential connections between the composition of...

News 13

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• Press Release
  
  Wyss Institute researchers demonstrate machine-guided engineering of AAV capsids for gene therapy
  November 28, 2019
• Translation News
  
  Harvard’s athlete-based next-generation probiotics technology licensed to FitBiomics
  September 5, 2019
• Press Release
  
  Discovery of performance-enhancing bacteria in the human microbiome
  June 24, 2019

Multimedia 4

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  Video/Animation
  AAV Capsid Engineering
  Wyss researchers have created a high-throughput platform to generate an Adeno-associated virus 2 (AAV2) library containing 200,000 variants, each carrying a distinct mutation in the virus capsid protein. Their analysis identified capsid changes that enhanced “homing” potential to specific organs in mice and virus viability, as well as a new protein hidden in the capsid-encoding...

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  Audio/Podcast
  Former DI Hoopster Searches For Athletic Boost In The Microbiome
  Former DI Hoopster Searches For Athletic Boost In The Microbiome was originally broadcast on WBUR’s Only a Game on August 4, 2017. The story features Wyss Core Faculty member George Church and Postdoctoral Fellow Jonathan Scheiman. The original broadcast story can be found here.

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  Video/Animation
  CRISPR-Cas: Molecular Recording
  In this video, Wyss Institute and Harvard Medical School researchers George Church and Seth Shipman explain how they engineered a new CRISPR system-based technology that enables the chronological recording of digital information, like that representing still and moving images, in living bacteria. Credit: Wyss Institute at Harvard University

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  Audio/Podcast
  Disruptive: Sports Genomics
  With 100 trillion cells in the human body, bacteria outnumber our own human cells 2 to 1. These bacteria make up one’s microbiome, and particularly bacteria in our guts affect all our key organ functions. They play a role in our health, development and wellness, including endurance, recovery and mental aptitude. In this episode of...