186 Results for 'Fundamental Research'
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Soft hydrogel electrodes for better, safer implants
Soft, conductive hydrogels match the physical properties of the human brain, enabling the creation of electrodes and implantable devices that can improve brain-machine interfaces while reducing the risk of injury.
Sparkle: Instant Biosensors for Real-Time Imaging
Sparkle is revolutionizing the binder assay industry by harnessing novel chemistry to create instant fluorescent biosensors for a wide variety of uses.
SPEAR: Ultrasensitive Protein Detection in Small Samples
Spear Bio uses a DNA nanotechnology-driven approach developed at the Wyss Institute that allows the sensitive detection of protein biomarkers in small samples using standard instruments to create new research and diagnostic assays. An ultra-sensitive assay detecting neutralizing antibodies against SARS-CoV-2 will be the first to be commercialized.
CircaVent: A Drug Discovery Platform for Mental Health Conditions
CircaVent is a novel drug discovery platform that combines predictive algorithms, high-throughput preclinical models, and human organoids to identify and test drugs that could treat mental health conditions like bipolar disorder.
OrbitSeq: A Collaborative Digital Hub for Life Sciences Data
OrbitSeq is a digital platform that empowers life sciences researchers to browse, upload, and analyze datasets, and easily collaborate with each other to bring science closer together and speed up the pace of discovery.
DNA Nanotechnology Tools: From Design to Applications
A suite of diverse, multifunctional DNA nanotechnological tools with unique capabilities and potential for a broad range of clinical and biomedical research areas. Our DNA nanotechnology devices were engineered to overcome specific bottlenecks in the development of new therapies and diagnostics, and to help further our understanding of molecular structures.
Audio/PodcastReimagining Infertility – An Interview with Christian KrammeChristian Kramme imagines a world where all people can have a child on their own time frame. Such “reproductive autonomy” is not the case today – infertility is a growing problem worldwide, and existing treatments like IVF are incredibly taxing on women’s bodies and too expensive for most of the global population to access. Listen...
Video/AnimationSeed-dependent crisscross DNA-origami slatsThis animation explains how the newly invented crisscross origami method can be used to build functionalized micron-scale DNA megastructures composed of many unique DNA origami “slats,” each with their own complexity and interactive properties. Credit: Wyss Institute at Harvard University
Video/AnimationReimagining Recovery and Pain Management After Her Injury: Megan SperryMegan Sperry is a Postdoctoral Fellow working on the Biostasis project to help develop therapeutics that could slow down biological time. In this video, she shares a personal story about an injury she suffered after years of figure skating and how she would Reimagine the World with better recovery outcomes and pain management after trauma....
Video/AnimationThe Vagina Chip: A New Preclinical Model for Research on Vaginal Epithelium Microbiome InteractionsThe Vagina Chip allows researchers to study a human model of the vaginal microbiome and develop new treatments for bacterial vaginosis and other conditions that threaten women’s health. Credit: Research Square
Video/AnimationLight-Seq: Light-Directed In Situ Barcoding of BiomoleculesThis animation explains how the Light-Seq technology works to barcode and deep-sequence selected cell populations in tissue samples, and how the team applied it to the analysis of distinct and rare cells in the mouse retina. Credit: Wyss Institute at Harvard University.
Audio/PodcastIlluminating Biological Context with Josie Kishi – Translation by Fifty YearsTechnologies like next-generation sequencing allow us to understand which RNA transcripts and proteins are expressed in biological tissues. However, it’s often equally important to understand how cells or molecules are positioned relative to one another! Whether it be a cell changing its shape, an organelle ramping up a metabolic process, or a DNA molecule traveling...