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Technologies 2

• FeCILL: Targeted Treatment for Severe Fungal Infections
  FeCILL is novel delivery vehicle for antifungal drugs that targets them right to the infection site and reduces harmful side effects in patients with severe fungal infections.
• FcMBL: Broad-Spectrum Pathogen Capture for Infectious Disease Diagnosis and Therapy
  The Problem Infectious diseases have plagued humanity for millennia, and the pathogens that infect and sicken humans are constantly evolving. Severe infections can cause sepsis, a life-threatening condition in which a patient’s immune system overreacts to the infection. The body starts to attack itself, which can lead to tissue damage, organ failure, and death. Sepsis...

News 5

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• Press Release
  
  A CRISPR fingerprint of pathogenic C. auris fungi
  January 14, 2026
• Press Release
  
  Wyss Institute team selected by DARPA-SHIELD program to develop first-of-its-kind biologically engineered broad-spectrum antimicrobial therapeutic
  September 16, 2024
• Press Release
  
  Accelerating pathogen identification in infants and children with bloodstream infections
  December 2, 2022

Multimedia 4

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  Video/Animation
  Arbor Armor: Could FcMBL Save The Peach Industry?
  Brown rot is one of the most devastating peach diseases, affecting both home and commercial orchards. When a member of the Wyss community discovered the disease on his peach tree, he mentioned his concerns with others in our community. What he didn’t expect was that his colleague potentially had a novel solution using an existing...

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  Video/Animation
  FeCILL: Reimagining How We Treat the Sickest Patients
  Opportunistic fungal infections usually only affect patients whose immune systems are compromised, but when they do, they are often deadly – the mortality rate for these infections can be as high as 25%. Existing antifungal treatments have high levels of toxicity, and can harm the patient more than they help. Researchers at the Wyss Institute...

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  Video/Animation
  Light-driven fine chemical production in yeast biohybrids
  Wyss Institute Core Faculty member Neel Joshi explains the concept of yeast biohybrids and how they can be used to harvest energy from light to drive the production of fine chemicals. Credit: Wyss Institute at Harvard University

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  Video/Animation
  Introduction to Sepsis Diagnostic
  What if we could diagnose sepsis in just hours, not days? Wyss Institute researchers discuss their approach to a rapid sepsis diagnostic. Credit: Wyss Institute at Harvard University