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Technologies 3

• T cell traps
  T cells, a subtype of white blood cells, play key roles in cell-mediated immunity, be it to fight infections and cancer or, when corrupted, to react against the body’s own cells in more than 80 autoimmune diseases, including type I diabetes, multiple sclerosis, rheumatoid arthritis and others. However, isolating disease-related T cells from the body...
• Implantable cancer vaccine
  The Wyss Institute’s implantable, biodegradable cancer vaccine leverages immunotherapeutic methods and could one day help overcome melanoma, other cancers, infectious diseases, auto-immune diseases, as well as vaccinate against specific peptides, proteins, or antigens. The implant is a biodegradable polymer scaffold containing growth factors and components of each patient’s tumors. The technology was initially designed to...
• Injectable Hydrogels for Better Drug Delivery
  Wyss researchers have developed a new approach to delivering drugs and therapeutic cells using biocompatible and biodegradable hydrogels made of alginate, a naturally occurring polysaccharide from brown algae. Injectable hydrogels could greatly improve clinical ability to provide extended drug release and controlled delivery throughout the body or at targeted local sites.  The method holds promising...

News 14

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• Press Release Sticky when wet: strong adhesive for wound healing
  July 27, 2017
• Community Seeing Is Believing: Therapeutic Cancer Vaccines
  April 5, 2017
• Press Release Setting a trap for autoimmunity
  April 10, 2017

Multimedia 3

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  Audio/Podcast
  Disruptive: Cancer Vaccine & Hydrogel Drug Delivery
  In this episode of Disruptive, Wyss Founding Core Faculty Member Dave Mooney discusses programmable nanomaterials approaches to fighting disease. Mooney explains how a cancer vaccine, developed by his team and currently in a clinical trial at the Dana-Farber Cancer Institute, can train one’s own immune system to target specific cancer cells. He also describes the...

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  Video/Animation
  Wyss Focus: Immuno-Materials
  Wyss Core Faculty, Dave Mooney, explains our new Immuno-Materials Focus Area, which adds a new dimension to immunotherapy in that it harnesses materials to make treatments more efficient and effective. These material-based systems are capable of modulating immune cells and releasing them into the body where they can treat diseases.

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  Video/Animation
  Introduction to Implantable Cancer Vaccine
  What if we could prevent and treat cancer with a simple vaccine? Related: https://wyss.harvard.edu/technology/implantable-cancer-vaccine/ Credit: Wyss Institute at Harvard University