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Technologies 64

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• Blood Clot Dx
  An ultra-sensitive triage test that identifies patients at risk for blood clots before they happen, enabling proactive treatment to reduce complications and deaths across a wide range of conditions.
• Injectable Hydrogel Adhesive for Improved Muscle Regeneration
  A super-strong, stretchy, and self-healing biomaterial that adheres to muscles and helps them heal faster after injury.
• Ropirio: Novel Treatments Targeting the Lymphatic System
  Ropirio is commercializing the world’s first drug that directly targets and reactivates lymph vessels, a portfolio of other lymph-targeting small molecules, and a preclinical platform for discovering more.
• Metabolically Labeled CAR-T Cells Against Cancer
  Through a simple and effective metabolic labeling approach, patient-derived T cells engineered to carry immune-enhancing cytokines on their surfaces could help expand adoptive T cell therapies to treatment of solid tumors and improve blood cancer therapies.
• Engineered Live Biotherapeutic Product (eLBP) to Protect the Microbiome from Antibiotics
  eLBP is a safe and cost-effective therapeutic for patients treated with beta-lactam antibiotics that safeguards against the loss of health-essential microbes while preventing the development and spread of antibiotic resistance.
• ReConstruct: Vascularized Tissue for Breast Reconstruction and Augmentation
  ReConstruct is a platform for growing, vascularizing, and implanting patient-derived tissues that enable safer breast reconstruction after cancer surgery.

Collaborations 3

• Brigham-Wyss DxA
  The Wyss DxA's clinical partners from Brigham and Women’s Hospital identify the most pressing unmet diagnostic needs, provide access to high-quality patient samples for our Biomarker Discovery Laboratory (BDL) and Brigham-Wyss DxA collaborators, and provide invaluable feedback and guidance on the engineering and validation of cost-effective, sensitive, and specific diagnostic tests.
• Biomarker Discovery Laboratory (BDL)
  Bridging the diagnostic gap from biomarker discovery to market-ready test kits and instruments through cutting-edge technology development and clinical collaboration.
• Wyss Brain Targeting Program
  Advancing brain delivery approaches that enable more safe and effective brain-targeted therapeutics.

News 426

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• Awards
  
  Wyss Institute-led collaboration awarded by ARPA-H PRINT program to engineer off-the-shelf, universal, transplant-ready graft for liver failure
  January 16, 2026
• Press Release
  
  A CRISPR fingerprint of pathogenic C. auris fungi
  January 14, 2026
• Research Spotlights
  
  First-in-human clinical trial of personalized, biomaterial-based cancer vaccine demonstrates feasibility, safety, and immune activation
  December 10, 2025

Multimedia 107

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  Video/Animation
  Atlantic Health Research Spotlight: Novel Anesthetics for Care in Battlefield and Disaster Area
  The Atlantic’s Health Summit returned to Boston in 2025 for their annual exploration of the urgent issues reshaping the healthcare landscape. The event showcased recent breakthroughs that are redefining medical practices and explored the challenges of scaling innovation and implementing sustainable solutions. Speakers explored early disease detection, novel anesthetics, pain management, AI and drug discovery,...

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  Video/Animation
  20ish Questions with Elliot Chaikof
  20-ish Questions shows a different side of Wyss Institute faculty, touching on aspects of their personal life, hobbies, interests, as well as their research. This round follows Elliot Chaikof, an Associate Faculty member at the Wyss Institute as well as the Chair of the Department of Surgery & Surgeon-in-Chief at Beth Israel Deaconess Medical Center....

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  Video/Animation
  Enhancing Lactation to Improve Infant and Maternal Health
  Lactation Biologics is developing a long-lasting, self-injectable treatment to help nursing mothers feed their babies naturally, helping them get the best nutrition possible in the face of climate disasters and supply chain disruptions. Credit: Wyss Institute at Harvard University

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  Video/Animation
  ReConstruct – 3D Bioprinted Vascularized Fat Tissues for Breast Reconstruction
  Breast cancer affects 15% of all women. Current options for breast reconstruction are insufficient and have poor patient outcomes. A research team at the Wyss Institute is addressing this clinical need by fabricating vascularized adipose tissue flaps for therapeutic use. Credit: Wyss Institute at Harvard University

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  Video/Animation
  Reimagine the World – Volume 2 – Diagnostics Accelerator
  Two clinicians collaborating with the Wyss Diagnostics Accelerator (DxA), Lise Johnson and Craig Hersh, as well as two members of the Wyss DxA Industrial Partnership Program, Nell Meosky Luo and Andy Levin, share how they would Reimagine the World and the personal stories that fuel their passion for the work they are doing. Credit: Wyss...

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  Video/Animation
  FeCILL: Reimagining How We Treat the Sickest Patients
  Opportunistic fungal infections usually only affect patients whose immune systems are compromised, but when they do, they are often deadly – the mortality rate for these infections can be as high as 25%. Existing antifungal treatments have high levels of toxicity, and can harm the patient more than they help. Researchers at the Wyss Institute...