202 Results for 'Medicine'
Manufacturing biomolecules ‘on the go’
Wyss Institute researchers have developed a biomolecular manufacturing method that can quickly and easily produce a wide range of vaccines, antimicrobial peptides and antibody conjugates while doing so anywhere, even in places without access to electrical power or refrigeration. The breakthrough could provide a life-saving workaround for making modern interventions available in remote areas. Today...
DNA Nanostructures for Drug Delivery
Researchers at the Wyss Institute have developed two methods for building arbitrarily shaped nanostructures using DNA, with a focus on translating the technology towards nanofabrication and drug delivery applications. One proprietary nanofabrication technique, called “DNA-brick self-assembly,” uses short, synthetic strands of DNA that work like interlocking Lego® bricks. It capitalizes on the ability to program...
Fluorescent In Situ Sequencing (FISSEQ)
Working copies of active genes — called messenger RNAs or mRNAs —translate the genetic information present in DNA into proteins within the cells’ multiple compartments. They are often positioned strategically within cells in ways that contribute critically to how cells and tissues grow, develop and function, and their mislocation can lead to disease development. To...
Ultra-Strong Flexible Biomaterials
Hydrogels are already being developed for use as scaffolds for tissue engineering, vehicles for drug delivery, actuators for optics and fluidics, and models for biological studies of tissue-supporting material called the extracellular matrix. But these water-rich polymer gels are weak; they rupture if stretched just a little, and they break easily compared with resilient biological...
Tethered Liquid Perfluorocarbon (TLP), a non-stick coating for medical devices
Every device implanted in the body or in contact with flowing blood faces two critical challenges that can threaten the life of the patient it is meant to help: blood clotting and bacterial infection. To confront this challenge, Wyss Institute researchers created a super-repellent, Thin Layer Perfluorocarbon (TLP) coating specifically designed to prevent clot formation...
Over 15 million Americans are at risk of anaphylaxis, a severe allergic reaction triggered by exposure to certain foods, materials, medications and insect bites. Every three minutes a food reaction sends someone to the emergency room. In most individuals, anaphylactic shock can be prevented by administering the counteracting drug, epinephrine. Yet, despite effective treatments, death from...
Oct 20, 2016, 6:00pm - 7:45pm
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Disruption in biotech can come in different forms, from new technologies that can change the face of medicine, to ideas and initiatives that can challenge the status quo. Boston has both of these in spades, with ambitious biotech startups bent on transforming drug development and industry leaders unafraid to tackle the sector’s toughest issues. But...