Application Area: Infectious Disease
109 Results for 'Infectious Disease'
Manufacturing biomolecules ‘on the go’
Wyss Institute researchers have developed a biomolecular manufacturing method that can quickly and easily produce a wide range of vaccines, antimicrobial peptides and antibody conjugates while doing so anywhere, even in places without access to electrical power or refrigeration. The breakthrough could provide a life-saving workaround for making modern interventions available in remote areas. Today...
Tethered Liquid Perfluorocarbon (TLP), a non-stick coating for medical devices
Every device implanted in the body or in contact with flowing blood faces two critical challenges that can threaten the life of the patient it is meant to help: blood clotting and bacterial infection. To confront this challenge, Wyss Institute researchers created a super-repellent, Thin Layer Perfluorocarbon (TLP) coating specifically designed to prevent clot formation...
Implantable cancer vaccine
The Wyss Institute’s implantable, biodegradable cancer vaccine leverages immunotherapeutic methods and could one day help overcome melanoma, other cancers, infectious diseases, auto-immune diseases, as well as vaccinate against specific peptides, proteins, or antigens. The implant is a biodegradable polymer scaffold containing growth factors and components of each patient’s tumors. The technology was initially designed to...
Pathogen Capture Technology for Infectious Disease Therapeutics and Diagnostics
Microbial contamination is the cause of life-threatening cases of sepsis, meningitis and multiple other infectious diseases that are a major cause of death world-wide. Equally prevalent are pathogenic contaminants in our environment, food, and manufacturing processes. In each case, the presence of microbial contaminants must be confirmed, and when they are found, they need to...
Clinical studies take years to complete and testing a single compound can cost more than $2 billion. Meanwhile, innumerable animal lives are lost, and the process often fails to predict human responses because traditional animal models often do not accurately mimic human pathophysiology. For these reasons, there is a broad need for alternative ways to...
SLIPS (Slippery Liquid-Infused Porous Surfaces)
The need for an inexpensive, super-repellent surface cuts across a vast swath of societal sectors—from refrigeration and architecture, to medical devices and consumer products. Most state-of-the-art liquid repellent surfaces designed in the last decade are modeled after lotus leaves, which are extremely hydrophobic due to their rough, waxy surface and the physics of their natural...