Discipline: Chemistry

Technologies 5

• Nixe: Bioinspired Sustainable and Water-repellent Textile Coating
  Next-generation PFAS-free water-repellent textile coating solution with utility for multiple industries and potential to dramatically reduce the use of “forever chemicals.”
• AminoX: Making Better Protein Drugs, Quicker and Cheaper
  AminoX enables protein drugs to only become active in the tumor microenvironment and not elsewhere in the body to avoid immune-related adverse effects in the body. By designing and building non-standard amino acids into strategic positions of protein drugs, AminoX provides tumor-specific, and longer-lasting target inhibition.
• directEsense: Revolutionizing Animal Diagnostic Testing at the Point-of-Care
  Electrochemical biosensors using a novel surface chemistry offer new opportunities for portable diagnostics with the potential to detect many disease biomarkers in animals and beyond.
• Injectable Alginate Hydrogels for Medical Applications
  One of the biggest challenges in medicine is getting a drug to the right part of the body at the right time. Even when the target site in the body is known, like a pain-causing injury or a cancerous tumor, most drugs are given as oral pills or intravenous infusions, which limits their effectiveness. In...
• MAGE: Multiplex Automated Genomic Engineering
  Developed at the Wyss Institute, the multiplex automated genome engineering (MAGE) technology harnesses the natural principles of evolution to do all the heavy lifting of genome design and automates these steps to dramatically shorten the time scale required to produce microbes with specialized functionalities for manufacturing, sensing and therapeutic applications. Genome engineering has a wide...

News 54

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• Community
  
  Sandy Elmehrath on Closing the Gender Health Gap by Driving Progress in Endometriosis Management and Care
  March 25, 2025
• Press Release
  
  DARPA-ABC program supports Wyss Institute-led collaboration toward deeper understanding of anesthesia and safe drugs enabling anesthesia without the need for extensive monitoring
  January 15, 2025
• Community
  
  Eliz Amar Lewis on Using Many Tools to Fight a Sophisticated Disease
  September 24, 2024

Multimedia 14

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  Video/Animation
  Atlantic Health Research Spotlight: Novel Anesthetics for Care in Battlefield and Disaster Area
  The Atlantic’s Health Summit returned to Boston in 2025 for their annual exploration of the urgent issues reshaping the healthcare landscape. The event showcased recent breakthroughs that are redefining medical practices and explored the challenges of scaling innovation and implementing sustainable solutions. Speakers explored early disease detection, novel anesthetics, pain management, AI and drug discovery,...

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  Video/Animation
  AminoX: Making Better Protein Drugs, Quicker and Cheaper
  A synthetic biology and advanced chemistry platform that efficiently incorporates non-standard amino acids by hacking the ubiquitous protein synthesis process. Credit: Wyss Institute at Harvard University

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  Video/Animation
  Catalytic Nanoarchitectures for Clean Air
  The Wyss Institute is developing a new type of coating for catalytic converters that, inspired by the nanoscale structure of a butterfly’s wing, can dramatically reduce the cost and improve the performance of air purification technologies, making them more accessible to all.  Credit: Wyss Institute at Harvard University  

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  Audio/Podcast
  Biofilms: Reprogramming Bacteria to Improve Lives
  Wyss Core Faculty member Neel Joshi and Postdoctoral Fellow Anna Duraj-Thatte discuss the intersection between synthetic biology and materials science as an underexplored area with great potential to positively affect our daily lives—applications ranging from manufacturing to medicine. Dr. Joshi outlines ways that his lab at the Wyss Institute is looking at reprogramming bacteria in...

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  Video/Animation
  3D Printing Ceramic Foam
  This video shows the 3D printing process that adds layer upon layer of the foam link to create a 3D porous ceramic honeycomb pattern. This new capability is an important step toward generating porous materials for lightweight structures, thermal insulation, tissue scaffolds and other applications. Credit: Lori Sanders

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  Video/Animation
  Bioprinting: The Kidney’s Proximal Tubules
  In this video, see how the Wyss Institute team has advanced bioprinting to the point of being able to fabricate a functional subunit of a kidney. Credit: Wyss Institute at Harvard University