124 Results for 'Microtechnology'
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MRBL: Next-Generation Gene Therapy for Molecular Skin Rejuvenation
The next-generation gene therapy for molecular skin rejuvenation combines a comprehensive target gene prediction with a novel transdermal delivery approach for therapeutic adenovirus-associated viruses. The platform targets monogenic disease indications in the skin, and extends the same targets to the treatment of common skin aging conditions.
FcMBL: Broad-Spectrum Pathogen Capture for Infectious Disease Diagnosis and Therapy
The Problem Infectious diseases have plagued humanity for millennia, and the pathogens that infect and sicken humans are constantly evolving. Severe infections can cause sepsis, a life-threatening condition in which a patient’s immune system overreacts to the infection. The body starts to attack itself, which can lead to tissue damage, organ failure, and death. Sepsis...
Single-Cell Encapsulation for Improved Cell Therapies
The Problem Mesenchymal stromal cells (MSCs) are valued for their ability to secrete compounds that modulate the body’s immune system, making them an attractive solution for existing problems with cell therapies including host-vs-graft disease and organ transplant rejections. However, MSCs are rapidly cleared from the body and can come under fire from the immune system....
RAPID: Testing for Food Contaminants
Contamination of food by microorganisms such as certain bacteria, viruses and fungi is a constant concern, with even miniscule amounts of certain species posing a risk for foods to become unsafe and spoiled during storage. Current safety and quality tests are often not sensitive enough to detect rare species, and because they first require the...
milliDelta: Millimeter-Scale Delta Robot
Delta robots are deployed in many industrial processes, including pick-and-place assemblies, machining, welding, and food packaging. Three individually controlled lightweight arms enable fast and accurate motion of an output platform in three directions. Roboticists have reduced the size of Delta robots for tasks in limited workspaces, but so far, using conventional manufacturing techniques and components,...
HAMR: Versatile Crawling Microrobot
Small or difficult-to-access spaces such as areas covered with rubble, or narrow pipes and engines can pose obstacles to search-and-rescue missions, repair works, or environmental and industrial monitoring. One solution for these problems could be small-sized robots that are able to navigate such spaces, transport payload, sense, and communicate. Wyss Institute researchers have developed a...
Video/AnimationThe Vagina Chip: A New Preclinical Model for Research on Vaginal Epithelium Microbiome InteractionsThe Vagina Chip allows researchers to study a human model of the vaginal microbiome and develop new treatments for bacterial vaginosis and other conditions that threaten women’s health. Credit: Research Square
Video/AnimationOrigami Miniature Surgical ManipulatorResearchers from the Wyss Institute, Harvard SEAS, and Sony have created the mini-RCM, a small surgical robot that can help surgeons perform delicate teleoperated procedures on the human body. Credit: Wyss Institute at Harvard University
Video/AnimationInterrogator: Human Organ-on-ChipsThis video describes the “Interrogator” instrument that can be programmed to culture up to 10 different Organ Chips and sequentially transfer fluids between their vascular channels to mimic normal human blood flow between the different organs of our body. Its integrated microscope enables the continuous monitoring of the tissues’ integrities in the individual organ chips...
Video/AnimationNanofiber-Reinforced Micro-ActuatorsThis video explains how two fabrication techniques, soft lithography and rotary jet spinning of nanofibers, are combined to create a new type of micro-actuator for the manipulation of small fragile objects in challenging environments. Credit: Wyss Institute at Harvard University
Video/AnimationMORPH: A new soft material microfabrication processWhat has the ability to move and show its colors, is made only of silicone rubber and manufactured at the millimeter scale? A soft robotic peacock spider. Researchers have combined three different manufacturing techniques to create a novel origami-inspired soft material microfabrication process that goes beyond what existing approaches can achieve at this small scale....
Video/AnimationHAMR: Robotic Cockroach for Underwater ExplorationsThis video shows how the HAMR can transition from land to water, paddle on the surface of water, or sink to the ground to start walking again just as it would on dry land. Credit: Yufeng Chen, Neel Doshi, and Benjamin Goldberg/Harvard University