Discipline: Synthetic Biology
231 Results for 'Synthetic Biology'
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HarborSite: Precise and Efficient Gene Editing for Next-Generation Gene Therapies
The HarborSite next-generation gene therapy platform enables integration of therapeutic genes into genomic safe harbors using highly specific and efficient recombinases to enable more predictable, safe and durable gene therapies.
Plastivores: Plastic-Degrading Super-Microbes and Enzymes
The Plastic Degradation project identifies microbes from natural sources that have a low-level ability to degrade multiple types of plastic. In the laboratory, with the help of synthetic biology, those microbes then are evolved into much more effective plastic-eating microbes that, in the future, could be globally deployed to decompose plastic waste.
Pancreatitis Tx: An Engineered Protein Treatment for Pancreatitis
First disease-modifying therapy that can be systemically applied to safely and effectively treat patients with different forms of pancreatitis.
Ichor: Reversing Aging
Ichor is addressing multiple age-related diseases by identifying genetic interventions that reprogram old cells to a younger state. Therapies based on these interventions could improve survival for cancer patients and long-term cardiovascular and neurological health.
Sparkle: Instant Biosensors for Real-Time Imaging
Sparkle is revolutionizing the binder assay industry by harnessing novel chemistry to create instant fluorescent biosensors for a wide variety of uses.
SPEAR: Ultrasensitive Protein Detection in Small Samples
Spear Bio uses a DNA nanotechnology-driven approach developed at the Wyss Institute that allows the sensitive detection of protein biomarkers in small samples using standard instruments to create new research and diagnostic assays. An ultra-sensitive assay detecting neutralizing antibodies against SARS-CoV-2 will be the first to be commercialized.
Video/AnimationHow can we feed the world?The current agricultural methods of feeding the world are not sustainable and already have dire consequences that will worsen as the Earth’s population continues to grow. Researchers at the Wyss Institute are working on various solutions that could help provide food for our future needs with a lower environmental impact. Credit: Wyss Institute at Harvard...
Video/AnimationSeed-dependent crisscross DNA-origami slatsThis animation explains how the newly invented crisscross origami method can be used to build functionalized micron-scale DNA megastructures composed of many unique DNA origami “slats,” each with their own complexity and interactive properties. Credit: Wyss Institute at Harvard University
Video/AnimationAcademic Entrepreneurship w/ Bob Langer & George Church – BIOS Roundtable #4George Church is a Core Faculty member at the Wyss Institute and a Professor at Harvard University. George leads Synthetic Biology at the Wyss Institute, where he oversees the directed evolution of molecules, polymers, and whole genomes to create new tools with applications in regenerative medicine and bio-production of chemicals. Among his recent work at...
Video/AnimationReimagining Neurodegenerative Disease Treatment for Her Grandfather: Mariana Garcia-CorralMariana Garcia-Corral is a Research Assistant studying brain organoids to help with the treatment of bipolar disorder. In this video, she shares a poignant personal story about her grandfather suffering from Lewy body dementia and how she would Reimagine a World with better neurodegenerative disease treatment. Credit: Wyss Institute at Harvard University
Video/AnimationEngineering Solutions to Confront the Climate CrisisAt the Wyss Institute, we are committed to tackling this existential climate crisis and are expanding our portfolio of sustainability research projects. Join us in reimagining a more sustainable future, together. Credit: Wyss Institute at Harvard University
Audio/PodcastXenotransplantation – The Naked Scientists Podcast with George ChurchAmidst the aftermath of COVID-19 waiting lists continue to grow for those in need of an organ transplant, whilst simultaneously in an American surgery a man receives the heart of a pig. Animal donors may be the answer to our shortage of available organs, but the procedure isn’t quite ready to become common place. Take...