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OrbitSeq: A Collaborative Digital Hub for Life Sciences Data
OrbitSeq is a digital platform that empowers life sciences researchers to browse, upload, and analyze datasets, and easily collaborate with each other to bring science closer together and speed up the pace of discovery.
EverActive: Strength Tracking Sensor for Sustainable Personalized Training
Exercise is key to good health, where aerobic and strength training are the two essential types. Industry has developed a number of aids and appliances ranging from sports watches to large stationary equipment to help track aerobic activities. Meanwhile, people still have to record manually their strength workouts and only few can do it, as...
FitBiomics is commercializing probiotic supplements based on unique combinations of microbes found in elite athletes’ guts to help optimize the health and function of all humans.
DNA Data Storage
The genetic material DNA has garnered considerable interest as a medium for digital information storage because its density and durability are superior to those of existing silicon-based storage media. For example, DNA is at least 1000-fold more dense than the most compact solid-state hard drive and at least 300-fold more durable than the most stable...
FISSEQ: Fluorescent In Situ Sequencing
Working copies of active genes — called messenger RNAs or mRNAs —translate the genetic information present in DNA into proteins within the cells’ multiple compartments. They are often positioned strategically within cells in ways that contribute critically to how cells and tissues grow, develop and function, and their mislocation can lead to disease development. To...
Microfluidic Hemostasis Monitor
The body’s ability to stop bleeding, also known as hemostasis, is critical for survival. For patients with blood clotting disorders, medical conditions requiring the use of anticoagulation or antiplatelet drugs, or who require treatment with extracorporeal devices that circulate their blood outside of the body, it is essential that care providers can rapidly monitor their...
Video/AnimationWyss Institute Brain Targeting ProgramThis animation explains how Wyss Institute researchers and their industry partners aim to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain. Credit: Wyss Institute at Harvard University.
Video/AnimationInterrogator: Human Organ-on-ChipsThis video describes the “Interrogator” instrument that can be programmed to culture up to 10 different Organ Chips and sequentially transfer fluids between their vascular channels to mimic normal human blood flow between the different organs of our body. Its integrated microscope enables the continuous monitoring of the tissues’ integrities in the individual organ chips...
Video/AnimationHip-only Soft Exosuit for both Walking and RunningThis video demonstrates the use of the hip-assisting exosuit in different natural environments, and shows how the robotic device senses changes in the gait-specific vertical movements of the center of mass during walking and running to rapidly adjust its actuation. Credit: Wyss Institute at Harvard University
Video/AnimationSoft Exosuit: Human-in-the-Loop Bayesian OptimizationResearchers from the Wyss Institute and Harvard SEAS have developed a human-in-the-loop Bayesian optimization method to personalize the hip assistance that a soft exosuit can provide. The optimized assistance helps reduce metabolic cost compared to walking without the device, or with the device not further personalized. Credit: Harvard Biodesign Lab/Harvard Agile Robotics Lab Learn more...
Video/AnimationPrimer Exchange ReactionIn this video, Jocelyn Kishi illustrates how Primer Exchange Reaction (PER) cascades work to autonomously create programmable long single-stranded DNA molecules. Credit: Wyss Institute at Harvard University.
Audio/PodcastFormer DI Hoopster Searches For Athletic Boost In The MicrobiomeFormer DI Hoopster Searches For Athletic Boost In The Microbiome was originally broadcast on WBUR’s Only a Game on August 4, 2017. The story features Wyss Core Faculty member George Church and Postdoctoral Fellow Jonathan Scheiman. The original broadcast story can be found here.