9 Results for 'Brain'
Engineering organoids to recapitulate brain tissue
The ability to derive and manipulate pluripotent stem cells has opened up new avenues for modeling biological systems in both healthy and diseased conditions. In order to more fully recapitulate the tissue microenvironment with its cell-cell, cell-extracellular matrix, and cell-niche interactions, it is essential to transition stem-cell culturing from monolayers to 3D structures. Self-organization of...
Video/AnimationGyrification: How the Brain Got its FoldsA team led by Wyss Institute Core Faculty member L. Mahadevan used numerical simulations and a physical gel model to answer an age-old question that has vexed scientists for years: how did the outer layer of the mammalian brain (gray matter) become so convoluted atop the brain’s inner white matter? It turns out that at...