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94 Results for 'Chemical Engineering'
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Technologies 12
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Rapid Metabolite-Sensing System for Blood Lactate
In emergency medicine, blood lactate levels are a reliable real-time indicator of the severity and mortality risk of conditions that occur as a result of poor blood circulation and oxygen supply to organs and tissues (hypoperfusion), such as in patients with sepsis, cardiac arrest, stroke, major trauma, cystic fibrosis and other conditions. Lactate levels also... -
Bone Marrow-Like Scaffolds for Accelerating Immune Reconstitution
Bone marrow transplants containing hematopoietic stem cells from an immune-compatible (“allogeneic”) donor can cure patients with otherwise fatal blood disorders including multiple myeloma and leukemias by reconstituting their entire immune systems after chemotherapy. However, following such a “hematopoietic stem cell transplantation” (HSCT), the restoration of T cell immunity – which depends on the production of... -
eRapid: Multiplexed Electrochemical Sensors for Fast, Accurate, Portable Diagnostics
Handheld electrochemical sensors have revolutionized at-home medical testing for diabetics, but they have not yet been successfully applied to diagnosing other conditions. These sensors are based on the activity of an enzyme, and there are only a limited number of enzymes that can be used to detect biomarkers of human disease. An alternative, much more... -
eRNA: Controlled Enzymatic RNA Oligonucleotide Synthesis
Synthetic RNA oligonucleotides designed as specific successions of the four nucleobases A, U, G, and C that mimic naturally occurring RNA species are the key components of diverse RNA-based therapies. These include RNA therapeutics that can partially or completely turn off the expression of disease-causing genes (antisense and interfering RNAs), help replace or supplement dysfunctional... -
Liquid-Infused Tympanostomy Tubes
Acute middle ear infections affect more than 700 million people each year, with children often experiencing the most recurrent and severe symptoms due to their underdeveloped physiology. By the age of three, 25-40 % of children have had at least three episodes of acute middle ear infection, which is commonly accompanied by excess fluids accumulating... -
Nanoarchitectures for Air Purification
Illnesses caused by air pollution are the third-leading cause of death in developing nations, and over 5 million people worldwide die every year from air pollution exposure. Catalytic converters, the most widely used air purification devices, convert the toxic gases and pollutants produced by fuel combustion into benign chemicals before the exhaust is released into...
News 56
Multimedia 26
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Audio/PodcastResearching Biosensors with Dr. Pawan JollyPoint of Care Medical Devices are the future! Pawan Jolly, Ph.D., Senior Staff Scientist at The Wyss Institute for Biologically Inspired Engineering at Harvard University talks with Jonah and Aryan of the Beyond the Books podcast about his research in the biosensor and medical device arena. They ask him about his latest COVID-19 focused project,...
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Video/AnimationBeating Back the Coronavirus: FDA-Approved Drug Repurposing PipelineWith the goal of rapidly repurposing FDA-approved drugs to treat COVID-19, the Wyss Institute is collaborating with the Frieman Lab at the University of Maryland Medical School and the tenOever Lab at the Icahn School of Medicine at Mount Sinai to establish a multidisciplinary pipeline that can rapidly predict, test, and validate potential treatments. Credit:...
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Video/AnimationeRapid: Bringing Diagnostics HomeSenior Research Scientist, Pawan Jolly, gives an overview of the eRapid Institute Project, a platform of multiplexed electrochemical sensors for fast, accurate, portable diagnostics. Credit: Wyss Institute at Harvard University
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Video/AnimationeRAPID: a Platform for Portable DiagnosticseRapid is an electrochemical sensing platform that uses a novel antifouling coating to enable low-cost, multiplexed detection of a wide range of biomolecules for diagnostics and other applications. Credit: Wyss Institute at Harvard
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Video/AnimationLiquid-Infused Tympanostomy TubesResearchers at the Wyss Institute have developed next-generation tympanostomy tubes with an innovative material design that significantly reduces biofouling, implant size, need for revision surgeries, and promotes drug delivery into the middle ear. Credit: Wyss Institute at Harvard University
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Video/AnimationLight-driven fine chemical production in yeast biohybridsWyss Institute Core Faculty member Neel Joshi explains the concept of yeast biohybrids and how they can be used to harvest energy from light to drive the production of fine chemicals. Credit: Wyss Institute at Harvard University