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Technologies 4

• FeCILL: Targeted Treatment for Severe Fungal Infections
  FeCILL is novel delivery vehicle for antifungal drugs that targets them right to the infection site and reduces harmful side effects in patients with severe fungal infections.
• OMNIVAX: Broadly Deployable Infection Vaccine Platform
  OMNIVAX is an immuno-material-based vaccine platform technology able to create safe and effective therapeutic and prophylactic vaccines against viral and bacterial threats. Its modular approach enables the rapid creation of vaccines for pathogens using known and unknown antigens. Current approaches include vaccines against some viral diseases.
• FcMBL: Broad-Spectrum Pathogen Capture for Infectious Disease Diagnosis and Therapy
  The Problem Infectious diseases have plagued humanity for millennia, and the pathogens that infect and sicken humans are constantly evolving. Severe infections can cause sepsis, a life-threatening condition in which a patient’s immune system overreacts to the infection. The body starts to attack itself, which can lead to tissue damage, organ failure, and death. Sepsis...
• RAPID: Testing for Food Contaminants
  Contamination of food by microorganisms such as certain bacteria, viruses and fungi is a constant concern, with even miniscule amounts of certain species posing a risk for foods to become unsafe and spoiled during storage. Current safety and quality tests are often not sensitive enough to detect rare species, and because they first require the...

News 6

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• Press Release
  
  Accelerating pathogen identification in infants and children with bloodstream infections
  December 2, 2022
• Press Release
  
  Biomaterial vaccines ward off broad range of bacterial infections and septic shock
  July 8, 2021
• Press Release
  
  A new weapon for the war on cancer: a broad-spectrum circulating tumor cell capture agent for diagnostics
  June 28, 2017

Multimedia 3

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  Video/Animation
  FeCILL: Reimagining How We Treat the Sickest Patients
  Opportunistic fungal infections usually only affect patients whose immune systems are compromised, but when they do, they are often deadly – the mortality rate for these infections can be as high as 25%. Existing antifungal treatments have high levels of toxicity, and can harm the patient more than they help. Researchers at the Wyss Institute...

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  Video/Animation
  OMNIVAX: Infection Vaccine Platform
  This video explains how OMNIVAX – an immuno-material-based vaccine technology can be used to rapidly create injectable vaccines against diverse viral and bacterial pathogens, and how the platform is used by the team to develop a vaccine against recurring urinary tract infections (UTIs) in their lead human application. Credit: Wyss Institute at Harvard University.

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  Video/Animation
  Introduction to Sepsis Diagnostic
  What if we could diagnose sepsis in just hours, not days? Wyss Institute researchers discuss their approach to a rapid sepsis diagnostic. Credit: Wyss Institute at Harvard University