Multimedia
- Multimedia Type
- Focus Areas
- 3D Organ EngineeringHighly functional, multiscale, vascularized organ replacements that can be seamlessly integrated into the body
- Bioinspired Therapeutics & DiagnosticsTherapeutic discovery and diagnostics development enabled by microsystems engineering, molecular engineering, computational design, and organ-on-a-chip in vitro human experimentation technology
- Computational Design & DiscoveryCombining predictive bioanalytics and machine learning with physical and mathematical modeling and simulation
- Diagnostics AcceleratorDeveloping new diagnostic technologies that solve important healthcare challenges through collaboration at the Wyss Institute with clinicians and industry partners
- Immuno-MaterialsMaterial-based systems capable of modulating immune cells ex vivo and in the human body to treat or diagnose disease
- Living Cellular DevicesRe-engineered living cells and biological circuits as programmable devices for medicine, manufacturing and sustainability
- Molecular RoboticsSelf-assembling molecules that can be programmed like robots to carry out specific tasks without requiring power
- Synthetic BiologyBreakthrough approaches to reading, writing, and editing nucleic acids and proteins for multiple applications, varying from healthcare to data storage
- Technology Areas
- 3D Printing
- Actuators
- Biomarker
- Building Materials
- Cell Therapy
- Diagnostics
- Disease Model
- DNA Nanostructures
- Drug Development
- Filtration & Separation
- Gene Circuits
- Imaging
- Immunotherapy
- Medical Devices
- Microbiome
- Microfabrication
- Microfluidics
- Microsystems
- Nanodevices
- Organs on Chips
- Robots
- Sensors
- Surface Coatings
- Therapeutics
- Vaccines
- Wearable Devices
- Disciplines
- Aging
- Architecture
- Biochemistry
- Bioinformatics
- Biotechnology
- Cell Biology
- Chemical Engineering
- Chemistry
- Computer Science
- Control
- Design
- Electrical Engineering
- Genetics
- Genome Engineering
- Immune Engineering
- Materials Science
- Mechanical Engineering
- Mechanobiology
- Medicine
- Microtechnology
- Nanobiotechnology
- Nanotechnology
- Pharmacology
- Physics
- Physiology
- Polymer Chemistry
- Regenerative Medicine
- Robotics
- Self Assembly
- Stem Cell Engineering
- Surgery
- Synthetic Biology
- Tissue Engineering
- Toxicology
- Application Areas
- Anti-aging
- Apparel
- Bacteria
- Balance & Motor Control
- Brain Disease
- Cancer
- Diabetes
- Drug Development
- Energy
- Fundamental Research
- Heart Disease
- Hemostasis
- Infectious Disease
- Inflammatory Diseases
- Intestinal Disease
- Kidney Disease
- Liver Disease
- Lung Disease
- Manufacturing
- Motor Control
- Personalized Medicine
- Rehabilitation
- Sepsis
- Stroke
- Sustainability
- Targeted Drug Delivery
- Toxicology
- Water
- Women's Health
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Audio/PodcastDisruptive: Synthetic BiologyWhat sorts of breakthroughs are possible by modifying an organism’s genome – something researchers are now able to do ever more cheaply and efficiently? Researchers around the world are already able to program microbes to treat waste water, generate electricity, manufacture jet fuel, create hemoglobin, and fabricate new drugs. What sounds like science fiction to... -
Video/AnimationSoft Robotic GloveThe soft robotic glove under development at the Wyss Institute could one day be an assistive device used for grasping objects, which could help patients suffering from muscular dystrophy, amyotrophic lateral sclerosis (ALS), incomplete spinal cord injury, or other hand impairments to regain some daily independence and control of their environment. This research is partially... -
Video/AnimationEnvironmental Impact: Chitin-Inhibiting Pesticides Called into QuestionChitin, a molecule that serves a purpose in the developmental biology of insects, fungi and shrimp, has long been a target of growth-inhibiting pesticides due to the belief that it did not exist in vertebrates. For decades, chitin-inhibiting pesticides have stunted the growth of insects and fungi to protect valuable crops. Now, research from the... -
Video/AnimationCas9: As a Transcriptional ActivatorIn this technical animation, Wyss Institute researchers instruct how they engineered a Cas9 protein to create a powerful and robust tool for activating gene expression. The novel method enables Cas9 to switch a gene from off to on and has the potential to precisely induce on-command expression of any of the countless genes in the... -
Video/AnimationMotion Capture LabThe Wyss InstituteÍs Motion Capture Lab is a state of the art facility designed to measure and analyze human motion. It allows Wyss Institute scientists and their collaborators to design, build and test assistive technologies, ultimately accelerating the translation of new devices to improve human lives. Credit: Wyss Institute at Harvard University -
Video/AnimationFluid GateIn this video, the fluid-based gating mechanism separates gas and water. The fluid-filled pores system leverages pressurization to control the opening and closing of its liquid gates, making it extremely precise at separating mixed materials. Credit: Wyss Institute at Harvard University -
Video/AnimationDNA NanoswitchesGel electrophoresis, a common laboratory process, sorts DNA or other small proteins by size and shape using electrical currents to move molecules through small pores in gel. The process can be combined with novel DNA nanoswitches, developed by Wyss Associate Faculty member Wesley Wong, to allow for the simple and inexpensive investigation of life’s most... -
Video/AnimationHuman Organs-On-ChipsWyss Institute researchers and a multidisciplinary team of collaborators have engineered microchips that recapitulate the microarchitecture and functions of living human organs, including the lung, intestine, kidney, skin, bone marrow and blood-brain barrier. These microchips, called ‘organs-on-chips’, offer a potential alternative to traditional animal testing. Each individual organ-on-chip is composed of a clear flexible polymer... -
Video/AnimationWyss Institute: Stay InspiredThe Wyss Institute has fueled a rapid uptick in translational technologies propelled into real-world applications, as was evident by the presentation of the year’s highlights during the Institute’s Sixth Annual Retreat. The Retreat was held November 17, 2014 at Boston’s Seaport World Trade Center and was attended by roughly 600 members of the Institute community.... -
Video/AnimationGene Editing Mechanism of CRISPR-Cas9In this animation, learn how CRISPR-Cas9 gene editing technology can be used to precisely disrupt and modify specific genes. Credit: Wyss Institute at Harvard University. -
Video/AnimationDesigning Fusion-Protein TherapiesIn this video, watch the new computational model in action as it simulates the behavior of a fusion-protein drug molecule after the targeting protein has attached to a cell. Developed by Wyss researchers, this model helps design more effective biologic drugs while eliminating drug candidates that are prone to causing side effects. Credit: Harvard’s Wyss... -
Video/AnimationToehold SwitchesIn this animation, Wyss Institute Postdoctoral Fellow Alex Green, Ph.D., the lead author of “Toehold Switches: De-Novo-Designed Regulators of Gene Expression”, narrates a step-by-step guide to the mechanism of the synthetic toehold switch gene regulator. Credit: Wyss Institute at Harvard University