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17 Results for 'David A. Weitz'
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Technologies 4
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Sugar-to-Fiber Enzyme for Healthier Food
In collaboration with Kraft Heinz, our sugar-to-fiber product can convert sugar in food products into prebiotic fiber in the human gut, reducing the amount of sugar absorbed into the bloodstream without altering the amount of sugar in existing food product recipes. -
Single-Cell Encapsulation for Improved Cell Therapies
The Problem Mesenchymal stromal cells (MSCs) are valued for their ability to secrete compounds that modulate the body’s immune system, making them an attractive solution for existing problems with cell therapies including host-vs-graft disease and organ transplant rejections. However, MSCs are rapidly cleared from the body and can come under fire from the immune system.... -
Microfluidic Drug Encapsulation
Because of their large molecular sizes and properties, biologic drugs, be it in the form of monoclonal antibodies that target disease-associated molecules or active proteins and enzymes that may correct deficiencies in the human body, have proven difficult to deploy in many cases. Their therapeutic effects on target cells and tissues often require high and... -
IBD ID: Finding Novel Anti-Inflammatory Drugs
Inflammatory Bowel Disease (IBD) disproportionately affects women, who also experience IBD symptoms differently than men. Through research with human Organ Chips, we identified the role of connective tissue in aggravating inflammation in the nearby intestinal cells of IBD patients. We will use this chip technology to enable rapid screening of stromal cells, crucial for understanding...