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38 Results for 'David J. Mooney'
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Technologies 4
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T cell traps
T cells, a subtype of white blood cells, play key roles in cell-mediated immunity, be it to fight infections and cancer or, when corrupted, to react against the body’s own cells in more than 80 autoimmune diseases, including type I diabetes, multiple sclerosis, rheumatoid arthritis and others. However, isolating disease-related T cells from the body... -
Ultra-Strong Flexible Biomaterials
Hydrogels are already being developed for use as scaffolds for tissue engineering, vehicles for drug delivery, actuators for optics and fluidics, and models for biological studies of tissue-supporting material called the extracellular matrix. But these water-rich polymer gels are weak; they rupture if stretched just a little, and they break easily compared with resilient biological... -
Implantable cancer vaccine
The Wyss Institute’s implantable, biodegradable cancer vaccine leverages immunotherapeutic methods and could one day help overcome melanoma, other cancers, infectious diseases, auto-immune diseases, as well as vaccinate against specific peptides, proteins, or antigens. The implant is a biodegradable polymer scaffold containing growth factors and components of each patient’s tumors. The technology was initially designed to... -
Injectable Hydrogels for Better Drug Delivery
Wyss researchers have developed a new approach to delivering drugs and therapeutic cells using biocompatible and biodegradable hydrogels made of alginate, a naturally occurring polysaccharide from brown algae. Injectable hydrogels could greatly improve clinical ability to provide extended drug release and controlled delivery throughout the body or at targeted local sites. The method holds promising...
News 29
Events 2
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May 23, 2017, 4:00pm - 5:00pm
Wyss Event
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Please join Dr. Morgan Alexander on Tuesday, May 23, from 4:00pm – 5:00pm as he discusses the development of bio-instructive materials and his work to improve upon them by screening 3D libraries.The biomaterials found in the clinic today are primarily chosen on the basis of their availability and mechanical properties rather than positive interactions with surrounding... Free and open to public -
Apr 5, 2017, 6:30pm - 7:30pm
Lecture
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Doors open at 6:00pm Talk begins at 6:30pm Wyss Core Faculty member David Mooney will present a talk with Mary Mooney, titled Seeing Is Believing: Therapeutic Cancer Vaccines. Marshalling a patient’s immune system to recognize and destroy cancerous cells is an exciting strategy to attack cancer, and this talk will explore materials that engage the immune system... Free and open to public
Multimedia 3
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Video/AnimationWyss Focus: Immuno-MaterialsWyss Core Faculty, Dave Mooney, explains our new Immuno-Materials Focus Area, which adds a new dimension to immunotherapy in that it harnesses materials to make treatments more efficient and effective. These material-based systems are capable of modulating immune cells and releasing them into the body where they can treat diseases. -
Video/AnimationTough GelA team at the Wyss Institute is honing a tough, rubbery hydrogel initially developed at Harvards School of Engineering and Applied Sciences. The gel is 90 percent water, yet it stretches without breaking to more than 20 times its original length and recoils like rubber, the researchers first reported in Nature in 2012. In fact,...
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Video/AnimationIntroduction to Implantable Cancer VaccineWhat if we could prevent and treat cancer with a simple vaccine? Related: https://wyss.harvard.edu/technology/implantable-cancer-vaccine/ Credit: Wyss Institute at Harvard University