160 Results for 'Harvard SEAS'
PhonoGraftTM: Biomimetic Hearing-restoration Technology
PhonoGraft is an easy-to-use, biomimetic device that stimulates a patient's eardrum to heal itself after perforation. This regenerative medicine approach can enable better and longer-lasting eardrum reconstruction, reducing the need for invasive surgeries and minimizing the risk of long-term hearing loss.
Microrobotic Laser-Steering Medical Device for Minimally Invasive Surgery
Endoscopy has proven extremely useful in many areas of medicine because it can be carried out with relatively few risks in a short time, and be used to diagnose and treat numerous diseases. In gastroenterology, endoscopies of the upper gastrointestinal tract (esophagus, stomach, first part of the small intestine; upper GI endoscopies) and lower gastrointestinal...
Cellular “Backpacks” to Slow Tumor Growth
Macrophages are the body’s multipurpose defense agents, patrolling for pathogens and engulfing cellular debris, foreign substances, microbes, and even cancer cells. But cancerous tumors have evolved an insidious defense mechanism: they can switch arriving macrophages from an anti-cancer state to a pro-cancer state, in which they help promote the tumor’s growth. As a result, attempts...
Rapid Metabolite-Sensing System for Blood Lactate
In emergency medicine, blood lactate levels are a reliable real-time indicator of the severity and mortality risk of conditions that occur as a result of poor blood circulation and oxygen supply to organs and tissues (hypoperfusion), such as in patients with sepsis, cardiac arrest, stroke, major trauma, cystic fibrosis and other conditions. Lactate levels also...
OMNIVAX: Broadly Deployable Infection Vaccine Platform
OMNIVAX is an immuno-material-based vaccine platform technology able to create safe and effective therapeutic and prophylactic vaccines against viral and bacterial threats. Its modular approach enables the rapid creation of vaccines for pathogens using known and unknown antigens. Current approaches include vaccines against some viral diseases.
Bone Marrow-Like Scaffolds for Accelerating Immune Reconstitution
An implantable bone marrow cryogel to accelerate the full reconstitution of the immune system, including T cell immunity, in patients that received chemotherapy and a bone marrow transplant. This could provide an off-the-shelf, material-based solution for patients with severe blood disorders whose immunity is recovering only slowly after treatment.
Mar 14, 2019, 4:30pmLecture
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Harvard John A. Paulson School of Engineering and Applied Sciences Topics in Bioengineering presents this lecture by Georg Duda, Wyss Institute Associate Faculty Member. Conceptually, our research aims at understanding endogenous cascades of tissue formation, cytokine signaling and cellular self-organization especially in bone. Mechanical straining and adaptation due to mechanical cues plays a central role... Free and open to public
Video/AnimationPhonoGraft: Programming the eardrum to repair itselfEardrum perforations are a widespread problem affecting millions worldwide. Current standard of care is invasive, involves harvesting an autologous tissue to patch the eardrum, and often requires to revision surgeries, while hearing outcomes remain unsatisfying. What if we could program the eardrum to repair itself after injury? Researchers at the Wyss Institute, Massachusetts Eye and...
Video/AnimationA Laser Steering Device for Robot-Assisted SurgeryResponding to an unmet need for a robotic surgical device that is flexible enough to access hard to reach areas of the G.I. tract while causing minimal peripheral tissue damage, Researchers at the Wyss Institute and Harvard SEAS have developed a laser steering device that has the potential to improve surgical outcomes for patients. Credit:...
Video/AnimationOrigami Miniature Surgical ManipulatorResearchers from the Wyss Institute, Harvard SEAS, and Sony have created the mini-RCM, a small surgical robot that can help surgeons perform delicate teleoperated procedures on the human body. Credit: Wyss Institute at Harvard University
Video/AnimationSmart Thermally Actuating TextilesSmart Thermally Actuating Textiles (STATs) are tightly-sealed pouches that are able to change shape or maintain their pressure even in environments in which the exterior temperature or airflow fluctuates. This soft robotics technology could be developed as novel components of rehabilitation therapies or to prevent tissue damage in hospital bed or wheelchair-bound individuals. Credit: Wyss...
Video/AnimationOMNIVAX: Infection Vaccine PlatformThis video explains how OMNIVAX – an immuno-material-based vaccine technology can be used to rapidly create injectable vaccines against diverse viral and bacterial pathogens, and how the platform is used by the team to develop a vaccine against recurring urinary tract infections (UTIs) in their lead human application. Credit: Wyss Institute at Harvard University.
Video/AnimationBeating Back the Coronavirus: Face Shields for Frontline Healthcare WorkersThere is a national shortage of personal protective equipment (PPE) for frontline healthcare workers battling the COVID-19 pandemic. Researchers from the Jennifer Lewis Lab at the Harvard School of Engineering and Applied Sciences and Wyss Institute at Harvard University self-assembled into a team manufacturing greatly needed face shields for local hospitals. Credit: Wyss Institute at...