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Soft hydrogel electrodes for better, safer implants
Soft, conductive hydrogels match the physical properties of the human brain, enabling the creation of electrodes and implantable devices that can improve brain-machine interfaces while reducing the risk of injury.
Metabolically Labeled CAR-T Cells Against Cancer
Through a simple and effective metabolic labeling approach, patient-derived T cells engineered to carry immune-enhancing cytokines on their surfaces could help expand adoptive T cell therapies to treatment of solid tumors and improve blood cancer therapies.
cSNAP: Eco-Friendly Air Conditioning
Our eco-friendly air conditioning technology is a low-carbon-footprint evaporative cooling system that reduces indoor air temperature without adding humidity.
Meat Alternative from Vegetable Protein
Nearly 60% of greenhouse gas emissions are linked to the production and processing of meat. Using Wyss-developed technology, an alternative meat can be made from vegetable protein that has the same taste and texture as animal products.
PhonoGraftTM: Biomimetic Hearing-restoration Technology
PhonoGraft is an eardrum-regenerating device that enables better and longer-lasting eardrum reconstruction, reducing the need for invasive surgeries and minimizing the risk of long-term hearing loss. Wyss startup Beacon Bio was acquired by Desktop Health, a healthcare business within Desktop Metal, Inc. which is further developing this technology towards commercialization with the former Wyss startup team leading the way.
Microrobotic Laser-Steering Medical Device for Minimally Invasive Surgery
Endoscopy has proven extremely useful in many areas of medicine because it can be carried out with relatively few risks in a short time, and be used to diagnose and treat numerous diseases. In gastroenterology, endoscopies of the upper gastrointestinal tract (esophagus, stomach, first part of the small intestine; upper GI endoscopies) and lower gastrointestinal...
Video/AnimationMetabolic T cell Labeling: simple and effective enhancement of therapeutic T cells with immune-stimulating cytokinesThis animation shows how the surface of patient-derived T cells is metabolically labeled with azido-sugar molecules that then can be used to attach immune-enhancing cytokines with the help of click chemistry. The approach could help expand adoptive T cell therapies to treatment of solid tumors. Credit: Wyss Institute at Harvard University
Video/AnimationSeed-dependent crisscross DNA-origami slatsThis animation explains how the newly invented crisscross origami method can be used to build functionalized micron-scale DNA megastructures composed of many unique DNA origami “slats,” each with their own complexity and interactive properties. Credit: Wyss Institute at Harvard University
Video/AnimationcSNAP: Reimagining CoolingWe are reimagining air-conditioners to meet increasing global cooling demand while combatting climate change. Our novel evaporative cooling technology, cSNAP, uses advanced materials science and design to make affordable, environmentally-positive eco-friendly air conditioners that work in most climates without the use of synthetic refrigerants. Credit: Wyss Institute at Harvard University
Video/AnimationJanus Tough Adhesives for Tendon RepairThere is a large unmet need for tendon regeneration therapies after injury. Building upon the tough gel adhesive technologies developed at the Wyss Institute at Harvard University and the Harvard School of Engineering and Applied Sciences, researchers from these institutions collaborated with a group at Novartis to create the Janus Tough Adhesives (JTAs). This two-sided...
Video/AnimationSoft Robots Aiding the Elderly and People with Physical ImpairmentsAn interdisciplinary team at Harvard University School of Engineering and the Wyss Institute at Harvard University is building soft robots for older adults and people with physical impairments. Examples of these robots are the Assistive Hip Suit and Soft Robotic Glove, both of which have been included in the 2021-2022 Smithsonian Institution exhibit entitled “FUTURES.”...
Video/AnimationPhonoGraft: Programming the eardrum to repair itselfEardrum perforations are a widespread problem affecting millions worldwide. Current standard of care is invasive, involves harvesting an autologous tissue to patch the eardrum, and often requires to revision surgeries, while hearing outcomes remain unsatisfying. What if we could program the eardrum to repair itself after injury? Researchers at the Wyss Institute, Massachusetts Eye and...
Mar 14, 2019, 4:30pmLecture
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Harvard John A. Paulson School of Engineering and Applied Sciences Topics in Bioengineering presents this lecture by Georg Duda, Wyss Institute Associate Faculty Member. Conceptually, our research aims at understanding endogenous cascades of tissue formation, cytokine signaling and cellular self-organization especially in bone. Mechanical straining and adaptation due to mechanical cues plays a central role... Free and open to public