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PhonoGraftTM: Biomimetic Hearing-restoration Technology
PhonoGraft is an eardrum-regenerating device that enables better and longer-lasting eardrum reconstruction, reducing the need for invasive surgeries and minimizing the risk of long-term hearing loss. Wyss startup Beacon Bio was acquired by Desktop Health, a healthcare business within Desktop Metal, Inc. which is further developing this technology towards commercialization with the former Wyss startup team leading the way.
Microrobotic Laser-Steering Medical Device for Minimally Invasive Surgery
Endoscopy has proven extremely useful in many areas of medicine because it can be carried out with relatively few risks in a short time, and be used to diagnose and treat numerous diseases. In gastroenterology, endoscopies of the upper gastrointestinal tract (esophagus, stomach, first part of the small intestine; upper GI endoscopies) and lower gastrointestinal...
Cellular “Backpacks” to Slow Tumor Growth
Macrophages are the body’s multipurpose defense agents, patrolling for pathogens and engulfing cellular debris, foreign substances, microbes, and even cancer cells. But cancerous tumors have evolved an insidious defense mechanism: they can switch arriving macrophages from an anti-cancer state to a pro-cancer state, in which they help promote the tumor’s growth. As a result, attempts...
Rapid Metabolite-Sensing System for Blood Lactate
In emergency medicine, blood lactate levels are a reliable real-time indicator of the severity and mortality risk of conditions that occur as a result of poor blood circulation and oxygen supply to organs and tissues (hypoperfusion), such as in patients with sepsis, cardiac arrest, stroke, major trauma, cystic fibrosis and other conditions. Lactate levels also...
OMNIVAX: Broadly Deployable Infection Vaccine Platform
OMNIVAX is an immuno-material-based vaccine platform technology able to create safe and effective therapeutic and prophylactic vaccines against viral and bacterial threats. Its modular approach enables the rapid creation of vaccines for pathogens using known and unknown antigens. Current approaches include vaccines against some viral diseases.
Bone Marrow-Like Scaffolds for Accelerating Immune Reconstitution
An implantable bone marrow cryogel to accelerate the full reconstitution of the immune system, including T cell immunity, in patients that received chemotherapy and a bone marrow transplant. This could provide an off-the-shelf, material-based solution for patients with severe blood disorders whose immunity is recovering only slowly after treatment.
Low-Cost Tactile Displays for the Blind and Visually Impaired
Age-related medical conditions are responsible for most cases of blindness and visual impairment worldwide. In 2015, there were an estimated 36 million blind people in the world, with an additional 217 million suffering from moderate to severe vision impairment. Over 80% of the visually impaired were older than 50, and this percentage is expected to...
EverActive: Strength Tracking Sensor for Sustainable Personalized Training
Exercise is key to good health, where aerobic and strength training are the two essential types. Industry has developed a number of aids and appliances ranging from sports watches to large stationary equipment to help track aerobic activities. Meanwhile, people still have to record manually their strength workouts and only few can do it, as...
cold-SNAP: Eco-Friendly Air Conditioning
As average global temperatures steadily climb, the worldwide demand for air conditioning is expected to triple by 2050. Conventional air conditioners, while now cheap to manufacture, still rely on low-efficiency mechanical vapor compression to cool and dehumidify air, making them one of the largest consumers of energy in industrialized countries. An alternative cooling method called...
Single-Cell Encapsulation for Improved Cell Therapies
Mesenchymal stromal cells (MSCs) are valued for their ability to secrete compounds that modulate the body’s immune system, making them an attractive solution for existing problems with cell therapies including host-vs-graft disease and organ transplant rejections. However, MSCs are rapidly cleared from the body and can come under fire from the immune system. Efforts to...
FOAMs: Soft Robotic Artificial Muscles
Soft robots, similar to living organisms, are made from compliant materials that allow them great flexibility and adaptability for tasks at the human-robot interface and elsewhere. To enable soft robotic missions in different industrial, exploratory, and medical settings, engineers are trying to equip them with artificial muscles that could enable them to move smoothly, efficiently...
Flexible Embedded Liquid Sensors
As we shift from carrying electronic devices in our pockets and purses to wearing them on our bodies, those devices need to be able to move and stretch with us, and to sense our movements in order to better do so. Such sensors must remain functional when stretched to several times their resting length, resist...
milliDelta: Millimeter-Scale Delta Robot
Delta robots are deployed in many industrial processes, including pick-and-place assemblies, machining, welding, and food packaging. Three individually controlled lightweight arms enable fast and accurate motion of an output platform in three directions. Roboticists have reduced the size of Delta robots for tasks in limited workspaces, but so far, using conventional manufacturing techniques and components,...
HAMR: Versatile Crawling Microrobot
Small or difficult-to-access spaces such as areas covered with rubble, or narrow pipes and engines can pose obstacles to search-and-rescue missions, repair works, or environmental and industrial monitoring. One solution for these problems could be small-sized robots that are able to navigate such spaces, transport payload, sense, and communicate. Wyss Institute researchers have developed a...
RoboBees: Autonomous Flying Microrobots
Inspired by the biology of a bee, researchers at the Wyss Institute are developing RoboBees, manmade systems that could perform myriad roles in agriculture or disaster relief. A RoboBee measures about half the size of a paper clip, weighs less that one-tenth of a gram, and flies using “artificial muscles” compromised of materials that contract when...