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38 Results for 'Virus'
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Technologies 6
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wFDCF Face Masks: A Wearable COVID-19 Diagnostic
The Problem The COVID-19 pandemic has made it starkly clear that the world lacks rapid, accurate diagnostic tests for pathogens. When patients arrive in a medical facility for treatment, the triage process is hindered by diagnostic tests that are inaccurate or take a long time to produce results. In addition, patients who are asymptomatic and... -
Broad-Spectrum RNA Therapeutic for COVID-19 and Influenza
The COVID-19 pandemic has killed more than two million people worldwide and death tolls continue to mount due to the lack of an effective prevention, cure, or widespread vaccine for the disease. Influenza viruses have been even more deadly in the past, and still cause hundreds of thousands of deaths every year. Seasonal flu vaccines... -
FcMBL: Broad-Spectrum Pathogen Capture for Infectious Diseases
Microbial infection is the cause of life-threatening cases of sepsis, meningitis and multiple other diseases that are major causes of death world-wide. Equally prevalent are pathogenic contaminants in our environment, food, and manufacturing processes. In each case, the presence of dangerous microbes must be confirmed, and when they are found, they need to be removed,... -
INSPECTR™: Direct-to-Consumer Molecular Diagnostic
INSPECTR™ is a molecular diagnostic platform that combines freeze-dried synthetic gene networks with cell-free expression systems to create novel biosensors that detect and report the presence of a target DNA or RNA molecule without the need for power or lab equipment. This technology was licensed by Wyss startup Sherlock Biosciences in 2019. -
AquaPulse: Portable Off-the-Grid Water Purification
Globally, more than 2 billion people are forced to use a drinking water source that is contaminated with bacteria, parasites, and other pathogens, and an estimated 502,000 people die each year from diarrhea as a result of unsafe water. While a majority of the world has access to improved water sources, many are often contaminated;... -
Human Organs-on-Chips
Organ Chips are microfluidic devices lined with living human cells for drug development, disease modeling, and personalized medicine. Launched in 2014, Wyss startup Emulate, Inc., is leveraging the Wyss Institute’s Organ Chip technology to mimic human organs in vitro, enabling faster, better, and cheaper drug development and insights into human health.
News 22
Multimedia 10
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Audio/PodcastPreventing the Next Pandemic with Organ ChipsIn search for strategies to curb pandemics, scientists strive to understand how pathogens slip past the immune system and wreak havoc on the body. To achieve this goal, researchers study viral infection in models that mimic how different cell types interact with each other, the immune system, or the environment. Organ-on-a-chip models combine tissue engineering...
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Video/AnimationeToehold: an RNA-detecting control element for use in RNA therapeutics, diagnostics and cell therapiesThis animation shows an example of an eToehold that detects and signals the presence of a specific viral RNA in a human cell. After the virus has injected its RNA into a host cell, the RNA acts as a “trigger RNA” by binding to a complementary sequence within the eToehold specifically engineered for its detection.... -
Video/AnimationInnovation Showcase – Wyss Institute: Wearable Technology with BiosensorsJay Sugarman talks with Peter Nguyen Ph.D., Luis Soenksen, Ph.D., and Nina Donghia–all of whom are associated with the Wyss Institute for Biologically Inspired Engineering at Harvard University. They’re on Innovation Showcase to inform viewers about the groundbreaking research they and their colleagues have been involved with related to the development of wearable technology as...
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Video/AnimationmiSherlock – Detecting COVID-19 Variants from SalivaDespite increasing vaccination rates, new, more-infectious variants of SARS-CoV-2 could prolong the COVID-19 pandemic. Researchers at the Wyss Institute at Harvard University and MIT have created a low-cost, CRISPR-based diagnostic platform that can detect SARS-CoV-2 variants in a patient’s saliva without the need for any additional equipment. The team hopes their device will enable more... -
Audio/PodcastTalking Biotech: COVID-19 Detection Masks and WearablesCOVID-19 is the spectrum of pathologies caused by the SARS-CoV2 virus. While the pandemic moves well into its second year, the importance of detection in populations cannot be overstated. However, testing methods typically include visiting testing centers, and it is hard to find a test that is both rapid and precise. Wyss Research Scientist Dr.... -
Video/AnimationBeating Back the Coronavirus – COVID-19 detecting face maskUsing freeze-dried cell free reactions and CRISPR-based biosensors, researchers at the Wyss Institute and M.I.T. have created a face mask that can detect the SARS-CoV-2 virus in a wearer’s breath in under 90 minutes. Such a mask would allow medical professionals to quickly identify COVID-19 patients and begin effective treatments. This facemask is a proof-of-concept...