Licensing Opportunities
Our most valuable disruptive technologies with real-world potential are matured through our Validation and Institute Project programs. These projects represent a subset of Wyss Institute technologies currently available for licensing. These technologies have been considerably de-risked by our Advanced Technology and Business Development teams and continue to be refined to advance their near-term translation into commercial products that will transform medicine and create a more sustainable world.
Explore Validation and Institute Projects
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VALIDATION PROJECT
Controlled Enzymatic RNA Oligonucleotide SynthesisSynthetic RNA oligonucleotides designed as specific successions of the four nucleobases A, U, G, and C that mimic naturally occurring RNA species are the key components of diverse RNA-based therapies. These include RNA therapeutics that can partially or completely turn off the expression of disease-causing genes (antisense and interfering RNAs), help replace or supplement dysfunctional... -
VALIDATION PROJECT
cold-SNAP: Eco-friendly air conditioningAs average global temperatures steadily climb, the worldwide demand for air conditioning is expected to triple by 2050. Conventional air conditioners, while now cheap to manufacture, still rely on low-efficiency mechanical vapor compression to cool and dehumidify air, making them one of the largest consumers of energy in industrialized countries. An alternative cooling method called... -
VALIDATION PROJECT
Single-Cell Encapsulation for Improved Cell TherapiesMesenchymal stromal cells (MSCs) are valued for their ability to secrete compounds that modulate the body’s immune system, making them an attractive solution for existing problems with cell therapies including host-vs-graft disease and organ transplant rejections. However, MSCs are rapidly cleared from the body and can come under fire from the immune system. Efforts to... -
VALIDATION PROJECT
AquaPulse: Portable Off-the-Grid Water PurificationGlobally, more than 2 billion people are forced to use a drinking water source that is contaminated with bacteria, parasites, and other pathogens, and an estimated 502,000 people die each year from diarrhea as a result of unsafe water. While a majority of the world has access to improved water sources, many are often contaminated;... -
VALIDATION PROJECT
abbieSense: Anaphylaxis DiagnosticThe molecule histamine plays a primary role in the anaphylaxis reaction, which is a major cause of illness and death in people with severe allergies. Histamine is a very small molecule composed of only seventeen atoms, making it a challenging target to detect. To date, no diagnostic test exists that can measure histamine levels accurately... -
VALIDATION PROJECT
Customizable scaffolds for faster, higher-quality T cell productionImmunotherapy, or tweaking the body’s own immune system to treat disease, is attracting significant attention in the medical field for its potential to offer long-lasting cures with fewer side effects than chemotherapy or other drugs. One type of immunotherapy involves isolating T cells (a type of white blood cell) from a patient’s body, sometimes modifying... -
INSTITUTE PROJECT
Soft Exosuits for Back Support During Strenuous TasksOver half a million workers in the manufacturing and construction industries are injured on the job each year, resulting in an estimated direct cost of $13.8 billion. Occupational back pain is the leading cause of injury and accounts for one-third of all musculoskeletal injuries, resulting in a median of eight days of missed work. Discussions... -
VALIDATION PROJECT
Nanoarchitectures for Air PurificationIllnesses caused by air pollution are the third-leading cause of death in developing nations, and over 5 million people worldwide die every year from air pollution exposure. Catalytic converters, the most widely used air purification devices, convert the toxic gases and pollutants produced by fuel combustion into benign chemicals before the exhaust is released into... -
VALIDATION PROJECT
Tough Gel AdhesivesA Band-Aid® adhesive bandage is an effective treatment for stopping external bleeding from skin wounds, but an equally viable option for internal bleeding does not yet exist. Surgical glues are often used inside the body instead of traditional wound closure techniques like stitches, staples, and clips because they reduce the patient’s time in the hospital... -
INSTITUTE PROJECT
JetValve for Heart RegenerationThe human heart beats approximately 35 million times every year, pumping blood into the circulation via four different heart valves. In more than four million people each year, heart valves fail for different reasons, including birth defects, age-related deteriorations and infections. At present, clinicians use either artificial prostheses or fixed animal and cadaver-sourced tissue to...