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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

December 29, 2025
Bioengineering & Translational Medicine
Viral vector-based gene therapies in the clinic: An update

Kyung Soo Park, Yong In Cho, Samir Mitragotri, Zongmin Zhao
January 23, 2026
Cell Reports
Scar-associated endothelial-stellate cellular crosstalk drives fibrosis resolution in MASH

Kenneth Li, Vardhman Kumar, Tran To, Álvaro González-Domínguez, Janvi Huria, Maylene Yu, Bruno Cogliati, Chittampalli N Yashaswini, Mark Miller, Andrea D Branch, Bruno Giotti, Alexander M Tsankov, Li Chen, Mathieu Petitjean, Jesse D Kirkpatrick, Sangeeta N Bhatia, Scott L Friedman, Shuang Wang
January 28, 2026
Nanoscale Horizons
Enhanced stability and sustained delivery of structurally dense DNA nanostructures via a biodegradable hydrogel platform

Youngjin Choi, Yeonju Song, Bo Kyung Cho, Sang Jin Baek, Jin Myeong Wang, Su Hyun Seok, William M Shih, Junsang Doh, Youngmee Jung, Ju Hee Ryu
December 18, 2025
Cell Biomaterials
Perfusable 3D models of ureteric bud and collecting duct tubules

Kayla J. Wolf, Ronald C. van Gaal, Sebastien G.M. Uzel, Jonathan E. Rubins, Aline N. Klaus, Amelie Printz, Pooja Nair, Katharina T. Kroll, Paul Stankey, Lisa M. Satlin, Jennifer A. Lewis
January 16, 2026
iScience
A human blood-brain barrier model reveals pericytes as critical regulators of viral neuroinvasion

Alexsia Richards, Andrew Khalil, Punam Bisht, Troy W Whitfield, Xinlei Gao, David Mooney, Lee Gehrke, Rudolf Jaenisch
January 19, 2026
Small
Light-Guided Molecular Patterning for High-Throughput Single-Molecule Mechanical Characterization

Hansol Choi, Andrew Ward, Wesley P. Wong
January 19, 2026
ACS Synthetic Biology
Oncogenic Alterations in PI3K Signaling Emulated Optogenetically Recapitulate Some Phenotypic Changes in Mammary Epithelia

Keith A. Gagnon, Veronica W. Hui, Terry Ching, Amy E. Stoddard, Esther Koh, Jeroen Eyckmans, Ahmad S. Khalil, Christopher S. Chen
January 21, 2026
Journal of Periodontal Research
Hydrogels in Periodontal and Craniofacial Regeneration: Current Applications and Next-Generation Biomaterials

Z. Gouveia, M. Diba, B. T. Yilmaz, Jae-Kook Cha, D. T. Wu, D. J. Mooney
January 20, 2026
Cell Stem Cell
Challenges and opportunities for human Organ Chips in FDA assessments and pharma pipelines

Donald E Ingber
January 12, 2026
ACS Applied Materials & Interfaces
Large-Area Flexible Photopolymerized Scaffolds: Fabrication and Application to Cardiomyocytes

Nazar Farid, Sogol Kianersi, Ayesha Sharif, Andrew C. Daly, M. Çağatay Karakan, Christopher S. Chen, Gerard M O’Connor
January 14, 2026
Nature Biomedical Engineering
Digital CRISPR-based diagnostics for quantification of Candida auris and resistance mutations

Justin C. Rolando, Anton Thieme, Nicole E. Weckman, Nayoung Kim, Helena de Puig, Xiao Tan, Emily Cotnoir, Vishnu Chaturvedi, James J. Collins & David R. Walt
January 2, 2026
Annals of Biomedical Engineering
A Portable, Active Abdominal Compression Binder for Orthostatic Intolerance: Design and Evaluation in Healthy Subjects

Vishnu S. Emani, Andreas Escher, Stephen P. Juraschek & Ellen T. Roche
January 4, 2026
Advanced Healthcare Materials
Human Progenitor T-Cell Differentiation Regulated by the Mechanical Resistance of Thymus-Mimetic Extracellular Matrices

Nicholas Jeffreys, Kyle T. Ruark, Joshua M. Price, Ella M. Serrano-Wu, Blake Hanan, Andrew S. Khalil, Wei-Hung Jung, Nuria Lafuente-Gómez, Christina M. Tringides, Ann Gao, Joshua M. Brockman, Andrew Lu, Izabela Zmirska, Kyle H. Vining, Junzhe Lou, Kwasi Adu-Berchie, Siyoon Kwon, Hamza Ijaz, Azeem Sharda, David T. Scadden, David J. Mooney
January 6, 2026
Nature Communications
Deep learning guided design of protease substrates

Carmen Martin-Alonso, Sarah Alamdari, Tahoura S. Samad, Kevin K. Yang, Sangeeta N. Bhatia & Ava P. Amini
January 13, 2026
Nucleic Acids Research
Single-molecule mechanostructural fingerprinting of nucleic acid conformations

Prakash Shrestha, Hans T Bergal, William M Shih, Wesley P Wong
December 24, 2025
Alzheimer's & Dementia
Transport target expression, a biomarker of brain shuttle fusion drug uptake, shows minimal influence of brain region, disease state, gender, and age, yet reveals significant individual variation

Ana R. Santa‐Maria, Sanjid Shahriar
December 30, 2025
Advanced Materials
Rotational Multimaterial 3D Printing of Soft Robotic Matter With Embedded Asymmetrical Pneumatics

Jackson K. Wilt, Natalie M. Larson, Jennifer A. Lewis
December 29, 2025
Trends in Biotechnology
Exploring substrate cofeeding for enhanced acetogenic C1 bioconversion with AneVO, a low-cost anaerobic parallel bioreactor platform

Kathryn O Hoyt, Guanyu Zhou, William Gasparrini, Patrick J Sliter, Daniel J Hart, Ahmad S Khalil, Benjamin M Woolston
January 18, 2026
Nature Biotechnology
Engineered base editors with reduced bystander editing through directed evolution

Ramiro M. Perrotta, Svenja Vinke, Raphaël Ferreira, Michaël Moret, Ahmed Mahas, Anush Chiappino-Pepe, Lisa M. Riedmayr, Anna-Thérèse Mehra, Louisa S. Lehmann & George M. Church
December 19, 2025
Small
A Simple, Ultrastable, and Cost-Effective Oxygen-Scavenging System for Long-Term DNA-PAINT Imaging

Rebecca T. Perelman, George M. Church, Johannes Stein