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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

August 27, 2025
Clinical & Experimental Allergy
Mass Spectrometry-Based Proteomics Analysis of Nasal Fluid Uncovers Differentially Expressed Proteins as Potential Biomarkers of Allergic Asthma

Jamie A. Rosado Alicea, Shad Morton, Alyson N. Brown, Bogdan Budnik, Ayobami Akenroye, Rushdy Ahmad, Tanya M. Laidlaw
August 7, 2025
Cell
A generative deep learning approach to de novo antibiotic design

Aarti Krishnan, Melis N Anahtar, Jacqueline A Valeri, Wengong Jin, Nina M Donghia, Leif Sieben, Andreas Luttens, Yu Zhang, Seyed Majed Modaresi, Andrew Hennes, Jenna Fromer, Parijat Bandyopadhyay, Jonathan C Chen, Danyal Rehman, Ronak Desai, Paige Edwards, Ryan S Lach, Marie-Stéphanie Aschtgen, Margaux Gaborieau, Massimiliano Gaetani, Samantha G Palace, Satotaka Omori, Lutete Khonde, Yurii S Moroz, Bruce Blough, Chunyang Jin, Edmund Loh, Yonatan H Grad, Amir Ata Saei, Connor W Coley, Felix Wong, James J Collins
August 18, 2025
mBio
Validation of human sensory neurons derived from inducible pluripotent stem cells as a model for latent infection and reactivation by herpes simplex virus 1

Hyung Suk Oh, Shu-Fan Chou, Priya Raja, Jaehoon Shim, Biswajit Das, Jean M. Pesola, Nicolás Romero, Jennifer S. Lee, Alex Ng, Elizabeth D. Buttermore, George Church, Clifford J. Woolf, Donald M. Coen, David M. Knipe
July 22, 2025
Advanced Materials Technologies
Microfluidic Production of Ultrathin, Handleable Collagen Sheets Exhibiting Toe-heel Tensile Behavior

Yuming Zhang, Shashi Malladi, Bangan Wang, Dong Ok Son, Boris Hinz, Elliot L. Chaikof, Axel Günther
August 15, 2025
Science Advances
Initiation of meiosis from human iPSCs under defined conditions through identification of regulatory factors

Merrick Pierson Smela, Jessica Adams, Carl Ma, Laura Breimann, Ursula Widocki, Bogdan Dobre, Toshihiro Shioda, and George M. Church
August 7, 2025
PNAS
Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues

Johannes Stein, Maria Ericsson, Michel Nofal, Lorenzo Magni, Sarah Aufmkolk, Ryan B McMillan, Laura Breimann, Conor P Herlihy, S Dean Lee, Andréa Willemin, Jens Wohlmann, Laura Arguedas-Jimenez, Peng Yin, Ana Pombo, George M Church, Chao-Ting Wu
July 15, 2025
iScience
A long-lasting prolactin stimulates galactopoiesis in mice

Kasia Kready, Kailyn E Doiron, Katherine Redfield Chan, Jeffrey C Way, Quincey Justman, Camille E Powe, Pamela A Silver
August 13, 2025
Advanced Science
Shear Stress Targeted Delivery of Nitroglycerin to Brain Collaterals Improves Ischaemic Stroke Outcome

Magdalena Litman, Sara Azarpeykan, Rebecca J Hood, Kristy Martin, Debbie Pepperall, Daniel Omileke, Fern Williams, Oktay Uzun, Deen Bhatta, Yuen K Yong, Alex Chan, Nicholas Hough, Sarah Johnson, Pablo Garcia Bermejo, Ferdinand Miteff, Carlos Garcia Esperon, Yvonne Couch, Alastair M Buchan, Neil J Spratt, Netanel Korin, Donald E Ingber, Daniel J Beard
August 14, 2025
Small Methods
The Effect of Mechanical Loading on Sprouting Angiogenesis from Engineered Macro-vessel Model

Lior Debbi, Oryan Karni Katovitch, Asaf Silverstein, Theodor Fuchs, Christopher S. Chen, Shulamit Levenberg
July 22, 2025
ACS Pharmacology & Translational Science
Mechanically Active and Antimicrobial Wound Closure Using an Adhesive Hydrogel-Elastomer

Cynthia Liu, Bersa Kelkai, David Wu, Alexander Tatara, Juan Cintron, David J. Mooney, Benjamin R. Freedman
July 31, 2025
Journal of the American Chemical Society
Ultrahigh-Throughput Multiplexed Screening of Purified Protein from Cell-Free Expression Using Droplet Microfluidics

Anqi Chen, Wentao Xu, Xinge Diana Zhang, Junming Lao, Xing Zhao, Karla Milcic, David A. Weitz
July 15, 2025
Physical Review Letters
Essay: Using Machine Learning for Antibiotic Discovery

Cesar de la Fuente-Nunez, James J Collins
August 5, 2025
Circulation
Ponatinib, But Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and Endothelial Cell TNF Signaling to Induce Atherosclerotic Plaque Inflammation, Myocardial Infarction, and Stroke

Alec Stepanian, BA, Richard J. Travers, MD, PhD, Angelina Tesfu, BS, Nicole L. Wolter, BS, Joshua J. Man, MD, PhD, Qing Lu, MD, Sohel Shamsuzzaman, PhD, Rebecca A. Deaton, PhD, Gary K. Owens, PhD, Christopher S. Chen, MD, PhD, and Iris Z. Jaffe, MD, PhD
July 30, 2025
Science Translational Medicine
Viral spike antigen clearance and augmented recovery in children with post-COVID multisystem inflammatory syndrome treated with larazotide

Lael M. Yonker, Abigail S. Kane, Zoe Swank, Lena Papadakis, Victoria Kenyon, Samuel Han, Rosiane Lima, Lauren B. Guthrie, Bryan Alvarez-Carcamo, Manuella Lahoud-Rahme, Duraisamy Balagur, Ryan W. Carroll, Josephine Lok, Chadi El Saleeby, David R. Walt, and Alessio Fasano
July 21, 2025
Developmental Cell
Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett’s Esophagus to adenocarcinoma

Michael K Strasser, David L Gibbs, Philippe Gascard, Joanna Bons, John W Hickey, Deng Pan, Joseph A Caruso, Xianhong Wang, Chira Chen-Tanyolac, Rosemary Bai, Christian M Schürch, Yuqi Tan, Sarah Black, Pauline Chu, Alican Ozkan, Nathan Basisty, Veena Sangwan, Jacob Rose, Samah Shah, Jordan B Burton, Sophie Camilleri-Broet, Pierre Olivier Fiset, Nicholas Bertos, Julie Berube, Haig Djambazian, Rui Li, Spyridon Oikonomopoulos, Daffolyn Rachael Fels Elliott, Sarah Vernovsky, Elee Shimshoni, Deborah Collyar, Ann Russell, Jiannis Ragoussis, Matthew D Stachler, James R Goldenring, Stuart A C McDonald, Donald E Ingber, Birgit Schilling, Garry P Nolan, Thea D Tlsty, Sui Huang, Lorenzo E Ferri
July 10, 2025
Computers in Biology and Medicine
Biomarker discovery for early breast cancer diagnosis using machine learning on transcriptomic data for biosensor development

Kalaumari Mayoral-Peña, Omar Israel González Peña, Natalie Artzi, Marcos de Donato
July 3, 2025
Cell
Optogenetics-enabled discovery of integrated stress response modulators

Felix Wong, Alicia Li, Satotaka Omori, Ryan S Lach, Jose Nunez, Yunke Ren, Sean P Brown, Vipul Singhal, Brent R Lyda, Taivan Batjargal, Ethan Dickson, Jose Roberto Rodrigues Reyes, Juan Manual Uruena Vargas, Shalaka Wahane, Hahn Kim, James J Collins, Maxwell Z Wilson
July 16, 2025
Clinical Infectious Diseases
Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic andiral Characteristics and Response to Dual and Extended Antiviral Therapy

Jessica S Little , Gregory E Edelstein , Zoe Swank , Manish C Choudhary , Ella Borberg , Cameron T Nutt , Hayden S Andrews , Muneerah Aleissa , Urwah Kanwal , Katherine D Friedman , Anna Piermattei , Hannah Levine , Rinki Deo , Aidan Eustace , Xiaofang Li , Scott Dryden-Peterson , Lisa Cosimi , Pritha Sen , Meghan A Baker , Ann E Woolley , Jonathan Z Li , David R Walt , Nicolas C Issa , Lindsey R Baden , Amy C Sherman
April 25, 2025
Nature Reviews Bioengineering
The emerging era of structural nanomedicine

Chad A. Mirkin, Milan Mrksich & Natalie Artzi
June 25, 2025
Stem Cells Translational Medicine
The need for an organoid manufacturing, preservation, and distribution center

Anthony Atala , John C Bischof , Christopher S Chen , John P Fisher , David L Hermanson , Charles L Howe , Walter C Low , Zhen Ma , David H McKenna , Sean P Palecek , Johnna S Temenoff , Brenda M Ogle