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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

July 9, 2026
Science
The CARM1 epigenetic enzyme inhibits cross-presenting dendritic cell function in cancer immunity

Xixi Zhang, Sherin Xirenayi, Ye Zhao, Wen Wang, Yuyang Han, Miguel Sobral, Shawn Kang, Chi Zhang, Graham L Barlow, Jason Pyrdol, Jae-Won Cho, Kun Huang, Xiaohan Ning, Martin Hemberg, Guo-Cheng Yuan, Eliezer M Van Allen, David J Mooney, Kai W Wucherpfennig
June 30, 2026
Frontiers in Global Women's Health
In vitro preclinical modeling of sex-specific biology and hormonal dynamics in women’s health: insights across multiple organs

Shiyan Tang, Jie Ji, Aakanksha Gulati, Yuncheng Man, Chaitra Belgur, Abidemi Junaid, Donald E Ingber
July 15, 2026
Nature
Ketogenic diet mediates intestinal tumorigenesis through lipids not ketones

Jessica E. S. Shay, Fangtao Chi, Constantine N. Tzouanas, Shixun Han, Xiao Zhang, Johanna Ten Hoeve, Kevin J. Williams, Seda Neptun, Tolga Sever, Isabela Fuentes, Sangeeta N. Bhatia, Gizem Calibasi-Kocal, Matthew G. Vander Heiden, Alex K. Shalek & Ömer H. Yilmaz
July 3, 2026
BMC Medical Genomics
Elective genomic sequencing for adults in research, clinical and commercial contexts

Michael D. Linderman, Sophia M. Adelson, Tala M. Berro, Jennifer L. Anderson, Scott D. Crawford, Tshaka J. Cunningham, Edward D. Esplin, Altovise T. Ewing-Crawford, Daiva E. Nielsen, Stacey Pereira, Tara Schmidlen, Heather Andrighetti, Steven B. Bleyl, George M. Church, Eden V. Haverfield, Madhuri Hegde, Lazaridis N. Konstantinos, Paul Kruszka, Debra Leonard, Thomas May, Molly McGinniss, Vaibhav Pandya, Eric E. Schadt, Bastian Greshake Tzovaras, Bethany Zettler, Amy L. McGuire, Robert C. Green & PeopleSeq Study Team
July 6, 2026
Advanced Science
A 3D Human Bone and Bone Marrow-on-a-Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Nina Stelzer, Melanie-Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler
June 25, 2026
Science
Antibiotics stimulate protein transfer to persister cells

Alice X. Wen, Julia Bos, Debojyoti Panda, Katelin M. Hagstrom, Shubham Singh, Shrawan Kumar Mageswaran, Xiaoli Wang, Bo Hu, Kobie T. Welc, Matthew B. Cooke, Jennifer A. Halliday, Laura Deus Ramire, Antoinette E. Martinez, Yi-Wei Chang, David A. Weitz, and Christophe Herman
May 22, 2026
biomolecules
DNA Cut-Ligation Cyclization Surpasses Jacobson-Stockmayer J-Factor Expectations by over Threefold

Roman Teo Oliynyk, George M Church
June 20, 2026
iScience
In vitro recapitulation of intramuscular mRNA vaccination with naive and recall antigens using a human lymphoid follicle chip platform

Yunhao Zhai, Min Wen Ku, Ka Yang, Aditya Patil, Pranav Prabhala, Liqun He, Yuncheng Man, Mizanur Rahman, Kavya Menon, Sven B. Spörri, Supriya Gharpure, Abdul Rahman Isaacs, Shay Ferdosi, Andrzej S. Pitek, Giulietta Maruggi, Sylvie Bertholet, Jessica Firestone, Kambiz Mousavi, Eric Miller, Kate Luisi, Caleb A. Hellman, LaTonya D. Williams, Georgia D. Tomaras, Peng Yin, Steven P. Gygi, Josie McAuliffe, Donald E. Ingber, Girija Goyal
June 22, 2026
Nature Communications
Probing the limits of genetic recoding using multi-omics-guided evolution

Akos Nyerges, Anush Chiappino-Pepe, Bogdan Budnik, Maximilien Baas-Thomas, Elissa Rhuby, Regan Flynn, Shirui Yan, Nili Ostrov, Min Liu, Meizhou Wang, Qingmei Zheng, Fangxiang Hu, Kangming Chen, Alexandra Rudolph, Dawn Chen, Jenny Ahn, Owen Spencer, Venkat Ayalavarapu, Angela Tarver, Miranda Harmon-Smith, Matthew Hamilton, Ian Blaby, Yasuo Yoshikuni, Behnoush Hajian, Adeline Jin, Balint Kintses, Monika Szamel, Viktoria Seregi, Yue Shen, Zilong Li & George M. Church
June 22, 2026
Nature Methods
Derivation of elephant induced pluripotent stem cells

Evan Appleton, Nataly Korover, Kyunghee Hong, Xochitl Ambriz-Peña, Yoshiaki Tanaka, Asaf Ashkenazy-Titelman, Cody Rasmussen-Ivey, Cristina Rodríguez-Caycedo, Ketaki Bhide, Hao Bai, Ana Queiroz, Jorgen W. Nelson, Grishma Rathod, Miles Morgan, Anthony Mastracci, Theodore M. Nelson, Gregory Knox, Brody McNutt, Nandini Malviya, Kairui Zhang, Amanda Kowalczyk, Austin Bow, Bryan McLendon, Jaroslav Slamecka, Krista Ryon, Jackie Proszynski, Nadia Houerbi, Ashley S. Kleinman, Chi-Lam Poon, Wendy Kiso, Matt James, In-Hyun Park, Charlie Gray, Virginia R. Pearson, Christopher E. Mason, Brandi L. Cantarel, Karl R. Koehler, Beth Shapiro, James Kehler, Ben Lamm, George Church & Eriona Hysolli
June 23, 2026
Advanced Drug Delivery Reviews
Human organ-on-a-chip technology as a catalyst for drug discovery

Ryan Posey, Alican Ozkan, Donald E Ingber
June 17, 2026
Science Translational Medicine
Deep learning–enabled discovery of antibiotics effective against Neisseria gonorrhoeae

Melis N. Anahtar, Jacqueline A. Valeri, Seyed Majed Modaresi, Aarti Krishnan, Nina M. Donghia, Samantha G. Palace, Erica J. Zheng, Aakanksha Gulati, Alicia Jorgenson, Abidemi Junaid, Parijat Bandyopadhyay, Andreas Luttens, Krishna Suresh, Paige Edwards, Felix Wong, Yu Zhang, Danilo Ritz, Margaux Gaborieau, Edmund Loh, Massimiliano Gaetani, Marie-Stephanie Aschtgen, Amir Ata Saei, Yonatan H. Grad, Donald E. Ingber, and James J. Collins
June 4, 2026
The Journal of the American Dental Association
Driving emerging technology to clinical impact

W Benton Swanson, David T Wu, Mutsumi Yoshida, Jeanne Ambruster, Charles S Sfeir, William R Wagner, David J Mooney, William V Giannobile, David H Kohn
June 5, 2026
Nature Communications
Programmable Nucleic Acid Sensing in Human Cells Using Circularizable ssDNA

Ahmed Mahas, Raphael Ferreira, Lisa M. Riedmayr & George M. Church
June 8, 2026
Scientific Reports
Probiotic intervention mitigates radiation-induced intestinal injury by alleviating oxidative stress in a human gut-on-a-chip

Nam Than, Tadanori Mammoto, Donald E. Ingber & Hyun Jung Kim
November 14, 2025
Bioengineering & Translational Medicine
Adoptive T-cell therapies in the clinic

Suyog Shaha, Leah Lourenco, Zongmin Zhao, Samir Mitragotri
February 25, 2026
Biological Theory
Mind Everywhere: A Framework for Conceptualizing Goal-Directedness in Biology and Other Domains-Part One

Michael Levin & David B. Resnik
February 25, 2026
Biological Theory
Mind Everywhere: A Framework for Conceptualizing Goal-Directedness in Biology and Other Domains-Part Two

Michael Levin & David B. Resnik
May 21, 2026
Nature Biomedical Engineering
Human inflammatory bowel disease-on-a-chip for modelling disease progression, cancer initiation and sex-specific effects

Alican Özkan, Gwenn E. Merry, David B. Chou, Ryan R. Posey, Anna Stejskalova, Karina Calderon, Megan Sperry, Joshua Piatok, Viktor Horvath, Lorenzo E. Ferri, Emanuela Carlotti, Stuart A. C. McDonald, Douglas J. Winton, Rocco Ricciardi, Liliana Bordeianou, Sean Hall, Girija Goyal & Donald E. Ingber
May 14, 2026
Science
Implantable living materials autonomously deliver therapeutics using contained engineered bacteria

Tetsuhiro Harimoto, Fernando Herrero Quevedo, Janis Zillig, Sanjay Schreiber, Yi Wu, Christine Heera Ahn, Tania To, Rohan Thakur, Alexander M. Tatara, Shawn Kang, Zheqi Chen, Nuria Lafuente-Gómez, Blake Hanan, Alexander Pauer, Shanda Lightbown, David A. Weitz, and David J. Mooney