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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

April 20, 2026
Advanced Science
A 3D In Vitro Model of the Human Hepatobiliary Junction

Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton-Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia
April 22, 2026
PNAS
Rotational 3D printing of active-passive filaments and lattices with programmable shape morphing

Mustafa K Abdelrahman, Jackson K Wilt, Yeonsu Jung, Rodrigo Telles, Gurminder K Paink, Natalie M Larson, Joanna Aizenberg, L Mahadevan, Jennifer A Lewis
April 23, 2026
Nature Communications
High-throughput single-vesicle imaging platform for direct extracellular vesicle profiling of human plasma

Chungmin Han, Arek V. Melkonian, Justin C. Rolando, Sara Whiteman & David R. Walt
April 17, 2026
Science Advances
Synthetic control of implanted engineered liver tissue growth

Amy E. Stoddard, Vardhman Kumar, Constantine N. Tzouanas, Veronica Hui, Jeffrey Li, Anisha Jain, Alanna Farrell, Sangeeta N. Bhatia, and Christopher S. Chen
April 2, 2026
Lab on a Chip
Stroke volume analog on a chip – in vitro hydrodynamic model of cardiac pumping efficiency

John F Zimmerman, Luke A MacQueen, Douglas Henze, Daniel J Drennan, Sean L Kim, Herdeline Ann M Ardoña, Suji Choi, Qianru Jin, Kevin Kit Parker
March 20, 2026
Device
A replenishable peritoneal implant for localized delivery and peritoneal fluid sampling in ovarian cancer

Aoibhin M Sheedy, Mihir Shetty, Anna Weis, Laura E Bendzick, Terran Stenger, Zhenya Ni, Philippa R Kennedy, Jacob A Myers, Niamh Ward, Lesley Trask, Hannah Prendeville, Joanne O'Dwyer, Michael O'Dwyer, Ellen T Roche, Garry P Duffy, Jeffrey S Miller, Melissa A Geller, Eimear B Dolan, Martin Felices
April 7, 2026
Lab on a Chip
A 3D microfluidic model of exchange between perfused blood and lymphatic microvascular networks

Delaney Gray-Scherr, Terry Ching, Katherine Beran, Sarah C Adams, Emily Davis, Abraham C I van Steen, Trisha Raman, Wilson W Wong, Jeroen Eyckmans, Christopher S Chen
April 8, 2026
Nature Communications
Hemostatic Tough Adhesives seal tissue and control hemorrhage

Daniel O. Kent, Phoebe S. Kwon, Kyle C. Wu, Matthew Torre, Hamza Ijaz, Favour Omafuvwe Obuseh, Brittany Pattison, Arthur Nedder, Francis McGovern, Jeremy Cannon, David J. Mooney & Benjamin R. Freedman
March 23, 2026
Chemical Science
A platform to design and optimise fluorogenic scFvs for detection of interleukin 33

Abigail E Reese, Utsa Karmakar, Margherita Restori, Marcela A Hermoso, George M Church, Erkin Kuru, Marc Vendrell
March 18, 2026
Nature
Synthetic circuits for cell ratio control

Bolin An, Tzu-Chieh Tang, Qian Zhang, Teng Wang, Yanyi Wang, Kesheng Gan, Kun Liu, Daniel L. Zhang, Yuzhu Liu, Yu Kui Pan, Min Yu, William M. Shaw, Qianyi Liang, Yaomin Wang, Christopher A. Vaiana, Chunbo Lou, Christopher A. Voigt, Timothy K. Lu, George M. Church & Chao Zhong
March 13, 2026
Journal of the American Chemical Society
Ultrasensitive Enzyme-Free Detection of Proteins on Magnetic Beads

Karan Malhotra, Louise L. Hansen, Samuel Han, Shira Roth, David R. Walt*
March 17, 2026
Nature Biotechnology
Manufacturing-aware generative models enable petascale synthesis of designed DNA

Eli N. Weinstein, Mattia G. Gollub, Andrei Slabodkin, Kerry Dobbs, Xiao-Bing Cui, Cameron L. Gardner, Ryan J. Grant, Kristina Gurung, Amira Bailey, Alan N. Amin, George M. Church & Elizabeth B. Wood
March 6, 2026
Clinical Trials
Developing a platform protocol for clinical trials evaluating interventions that target proposed mechanisms of Long COVID: RECOVER-VITAL

Kanecia O Zimmerman, Richard Whitley, Sean O'Brien, David R Walt, Bruce D Levy, Christine Maughan, Marta Cerda, Rachel Olson, Lucinda Bateman, Cyndya A Shibao, Barry Make, David Knopman, Susan Redline, Leonard A Jason, Mehul S Suthar, Phillip Low, Tracy L Nolen, Craig Reist, Lisa Berdan, Lindsey R Baden
March 7, 2026
Advanced Science
Heuristically Adaptive Diffusion-Model Evolutionary Strategy

Benedikt Hartl, Yanbo Zhang, Hananel Hazan, Michael Levin
March 10, 2026
Communications Medicine
Antigen heterogeneity in the development and clinical validation of a multiplexed urine test for tuberculosis

Tyler J. Dougan, Shira Roth, Liangxia Xie, Sydney D’Amaddio & David R. Walt
January 27, 2026
Nature Reviews Materials
Delivering living medicines with biomaterials

Tetsuhiro Harimoto, Wei-Hung Jung, David Mooney
March 11, 2026
Nature Biomedical Engineering
DNA origami vaccine nanoparticles improve humoral and cellular immune responses to infectious diseases

Yang C. Zeng, Olivia J. Young, Qiancheng Xiong, Longlong Si, Min Wen Ku, Sylvie G. Bernier, Hawa Dembele, Giorgia Isinelli, Tal Gilboa, Zoe Swank, Su Hyun Seok, Anjali Rajwar, Amanda Jiang, Yunhao Zhai, LaTonya D. Williams, Caleb A. Hellman, Chris M. Wintersinger, Amanda R. Graveline, Andyna Vernet, Melinda Sanchez, Sarai Bardales, Georgia D. Tomaras, Ju Hee Ryu, Ick Chan Kwon, Girija Goyal, Donald E. Ingber & William M. Shih
March 11, 2026
Nature
Immune evasive DNA donors and recombinases license kilobase-scale writing

Connor J. Tou, Keqiang Xie, Joana Ferreira da Silva, Pazhanichamy Kalailingam, Eliz Amar-Lewis, David Rufino-Ramos, William Sawyer, Madeline L. Eller, Jakob Starzyk, Ishita Majumdar, Jiao Wang, Danna Lee, Shaobo Yang, Ronald J. Meis, Gary A. Dahl, Jiahe Li, Richard Shan, Natalie Artzi, Patricia L. Musolino, Hao Wu & Benjamin P. Kleinstiver
February 18, 2026
Cell Systems
Generative AI for synthetic biology: Designing biological parts, circuits, and genomes

Nayoung Kim, Giuliano De Carluccio, Kehan Zhang, James J Collins
February 19, 2026
Nature Communications
FATE-MAP predicts teratogenicity and human gastrulation failure modes by integrating deep learning and mechanistic modeling

Joseph Rufo, Chongxu Qiu, Dasol Han, Naomi Baxter, Gabrielle Daley, Jasmine Dhillon, Felix Wong, James J. Collins & Maxwell Z. Wilson