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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

December 11, 2024
Nature
Sacrificial capillary pumps to engineer multiscalar biological forms

Subramanian Sundaram, Joshua H. Lee, Isabel M. Bjørge, Christos Michas, Sudong Kim, Alex Lammers, João F. Mano, Jeroen Eyckmans, Alice E. White & Christopher S. Chen
December 2, 2024
Bioessays
The Multiscale Wisdom of the Body: Collective Intelligence as a Tractable Interface for Next-Generation Biomedicine

Michael Levin
November 22, 2024
Journal of Controlled Release
Backpack-carrying macrophage immunotherapy for periodontitis

Mayuka Nakajima, Neha Kapate, John R Clegg, Mayumi Ikeda-Imafuku, Kyung Soo Park, Ninad Kumbhojkar, Vinny Chandran Suja, Supriya Prakash, Lily Li-Wen Wang, Koichi Tabeta, Samir Mitragotri
November 21, 2024
Nature Methods
Accurate RNA 3D structure prediction using a language model-based deep learning approach

Tao Shen, Zhihang Hu, Siqi Sun, Di Liu, Felix Wong, Jiuming Wang, Jiayang Chen, Yixuan Wang, Liang Hong, Jin Xiao, Liangzhen Zheng, Tejas Krishnamoorthi, Irwin King, Sheng Wang, Peng Yin, James J. Collins & Yu Li
May 4, 2024
Bioengineering & Translational Medicine
Antibody drug conjugates in the clinic

Edidiong Udofa, Disha Sankholkar, Samir Mitragotri, Zongmin Zhao
May 16, 2024
Bioengineering & Translational Medicine
Hydrogels in the clinic: An update

John R. Clegg, Kolade Adebowale, Zongmin Zhao, Samir Mitragotri
May 1, 2024
Bioengineering & Translational Medicine
Hemostats in the clinic

Maithili Joshi, Zongmin Zhao, Samir Mitragotri
October 2, 2024
Matter
Stiff Hydrogel Encapsulation Retains Mesenchymal Stem Cell Stemness for Regenerative Medicine

Bo Li, Liyuan Zhang, Yuan Yin, Anqi Chen, Bo Ri Seo, Junzhe Lou, David J Mooney, David A Weitz
November 18, 2024
PNAS
IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines

Miguel C. Sobral, Laura Cabizzosu, Shawn J. Kang, Kyle Ruark, Alex J. Najibi, Ryan S. Lane, Einat Vitner, Hamza Ijaz, Maxence O. Dellacherie, Mason T. Dacus, Christina M. Tringides, Irene de Lázaro, Mikaël J. Pittet, Sören Müller, Shannon J. Turley, and David J. Mooney
November 18, 2024
Advanced Science
Matrix Architecture and Mechanics Regulate Myofibril Organization, Costamere Assembly, and Contractility in Engineered Myocardial Microtissues

Samuel J. DePalma, Javiera Jilberto, Austin E. Stis, Darcy D. Huang, Jason Lo, Christopher D. Davidson, Aamilah Chowdhury, Robert N. Kent III, Maggie E. Jewett, Hiba Kobeissi, Christopher S. Chen, Emma Lejeune, Adam S. Helms, David A. Nordsletten, Brendon M. Baker
November 11, 2024
Scientific Reports
Multicellular adaptation to electrophysiological perturbations analyzed by deterministic and stochastic bioelectrical models

Javier Cervera, Michael Levin & Salvador Mafe
October 7, 2024
Open Forum Infectious Diseases
Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission During the Omicron Era in Massachusetts: A Prospective, Case-Ascertained Study Using Genomic Epidemiology

Jaspreet Banga, Taylor Brock-Fisher, Brittany A Petros, Eric Y Dai, Ariana T Leonelli, Sabrina T Dobbins, Katelyn S Messer, Audrey B Nathanson, Amelia Capone, Nancy Littlehale, Viola Appiah-Danquah, Siang Dim, Gage K Moreno, Maura Crowther, Katherine C DeRuff, Bronwyn L MacInnis, Michael Springer, Pardis C Sabeti, Kathryn E Stephenson
November 12, 2024
Biomaterials Science
Photoinitiator-free light-mediated crosslinking of dynamic polymer and pristine protein networks

Riccardo Rizzo, Dylan M Barber, Jackson K Wilt, Alexander J Ainscough, Jennifer A Lewis
November 8, 2024
Science Advances
A coronaviral pore-replicase complex links RNA synthesis and export from double-membrane vesicles

Anan Chen, Ana-Mihaela Lupan, Rui Tong Quek, Stefan G Stanciu, Mihaela Asaftei, George A Stanciu, Kierra S Hardy, Taciani de Almeida Magalhães, Pamela A Silver, Timothy J Mitchison, Adrian Salic
November 8, 2024
Nature Methods
Induced pluripotent stem cell-derived cardiomyocyte in vitro models: benchmarking progress and ongoing challenges

Jourdan K. Ewoldt, Samuel J. DePalma, Maggie E. Jewett, M. Çağatay Karakan, Yih-Mei Lin, Paria Mir Hashemian, Xining Gao, Lihua Lou, Micheal A. McLellan, Jonathan Tabares, Marshall Ma, Adriana C. Salazar Coariti, Jin He, Kimani C. Toussaint Jr., Thomas G. Bifano, Sharan Ramaswamy, Alice E. White, Arvind Agarwal, Emma Lejeune, Brendon M. Baker & Christopher S. Chen
October 23, 2024
10th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob)
Deep-Learning Based Lumbar Moment Estimation During Exosuit Augmented Lifting with Variable Loading Conditions

Philipp Arens; D. Adam Quirk; Conor J. Walsh
October 30, 2024
Nature
Temporal recording of mammalian development and precancer

Mirazul Islam, Yilin Yang, Alan J. Simmons, Vishal M. Shah, Krushna Pavan Musale, Yanwen Xu, Naila Tasneem, Zhengyi Chen, Linh T. Trinh, Paola Molina, Marisol A. Ramirez-Solano, Iannish D. Sadien, Jinzhuang Dou, Andrea Rolong, Ken Chen, Mark A. Magnuson, Jeffrey C. Rathmell, Ian G. Macara, Douglas J. Winton, Qi Liu, Hamim Zafar, Reza Kalhor, George M. Church, Martha J. Shrubsole, Robert J. Coffey & Ken S. Lau
November 6, 2024
Nature Computational Science
Deep generative design of RNA aptamers using structural predictions

Felix Wong, Dongchen He, Aarti Krishnan, Liang Hong, Alexander Z. Wang, Jiuming Wang, Zhihang Hu, Satotaka Omori, Alicia Li, Jiahua Rao, Qinze Yu, Wengong Jin, Tianqing Zhang, Katherine Ilia, Jack X. Chen, Shuangjia Zheng, Irwin King, Yu Li & James J. Collins
October 24, 2024
Nature Cell Biology
Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option

Marina Uroz, Amy E. Stoddard, Bryan P. Sutherland, Olivia Courbot, Roger Oria, Linqing Li, Cara R. Ravasio, Mai T. Ngo, Jinling Yang, Juliann B. Tefft, Jeroen Eyckmans, Xue Han, Alberto Elosegui-Artola, Valerie M. Weaver & Christopher S. Chen
October 28, 2024
PNAS
Tuning porosity of macroporous hydrogels enables rapid rates of stress relaxation and promotes cell expansion and migration

Bryan A Nerger, Kirti Kashyap, Brendan T Deveney, Junzhe Lou, Blake F Hanan, Qi Liu, Andrew Khalil, Tenzin Lungjangwa, Maria Cheriyan, Anupam Gupta, Rudolf Jaenisch, David A Weitz, L Mahadevan, David J Mooney