Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

July 24, 2024
Experimental Dermatology
Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent

Li Li, Irshad Hajam, Jean S. McGee, Zhengkuan Tang, Ye Zhang, Nikil Badey, Esther Mintzer, Zhenrui Zhang, George Y. Liu, George M. Church, Yu Wang
July 15, 2024
Nature Communications
Efficient and reproducible generation of human iPSC-derived cardiomyocytes and cardiac organoids in stirred suspension systems

Maksymilian Prondzynski, Paul Berkson, Michael A. Trembley, Yashasvi Tharani, Kevin Shani, Raul H. Bortolin, Mason E. Sweat, Joshua Mayourian, Dogacan Yucel, Albert M. Cordoves, Beatrice Gabbin, Cuilan Hou, Nnaemeka J. Anyanwu, Farina Nawar, Justin Cotton, Joseph Milosh, David Walker, Yan Zhang, Fujian Lu, Xujie Liu, Kevin Kit Parker, Vassilios J. Bezzerides & William T. Pu
July 14, 2024
Biochemical and Biophysical Research Communications
Stress sharing as cognitive glue for collective intelligences: A computational model of stress as a coordinator for morphogenesis

Lakshwin Shreesha, Michael Levin
July 12, 2024
Nature Biotechnology
Template-independent enzymatic synthesis of RNA oligonucleotides

Daniel J. Wiegand, Jonathan Rittichier, Ella Meyer, Howon Lee, Nicholas J. Conway, Daniel Ahlstedt, Zeynep Yurtsever, Dominic Rainone, Erkin Kuru & George M. Church
July 5, 2024
Nucleic Acids Research
Multiplexed in situ protein imaging using DNA-barcoded antibodies with extended hybridization chain reactions

Yu Wang, Xiaoyu Liu, Yitian Zeng, Sinem K Saka, Wenxin Xie, Isabel Goldaracena, Richie E Kohman, Peng Yin, George M Church
July 5, 2024
Angiogenesis
A streamlined method to generate endothelial cells from human pluripotent stem cells via transient doxycycline-inducible ETV2 activation

Allen Chilun Luo, Jiuhai Wang, Kai Wang, Yonglin Zhu, Liyan Gong, Umji Lee, Xiang Li, Daniel M. Tremmel, Ruei-Zeng Lin, Donald E. Ingber, James Gorman & Juan M. Melero-Martin
July 5, 2024
Progress in Biophysics and Molecular Biology
Bioelectric pharmacology of cancer: A systematic review of ion channel drugs affecting the cancer phenotype

Karina Kofman, Michael Levin
June 20, 2024
Molecular Cell
A high-throughput synthetic biology approach for studying combinatorial chromatin-based transcriptional regulation

Miguel A Alcantar, Max A English, Jacqueline A Valeri, James J Collins
June 21, 2024
Biofabrication
A perfusable, vascularized kidney organoid-on-chip model

Katharina Kroll, Kimberly Homan, Sébastien G M Uzel, Mariana Mata, Kayla Wolf, Jonathan Eric Rubins, Jennifer A Lewis
June 22, 2024
Mass Spectrometry Based Single Cell Proteomics
Single-Cell Proteomics Analysis with Tecan Uno and SCREEN Workflow

Michael Lewandowski, Shad Morton, Matthew Blake, Erica Squires, Rushdy Ahmad, David R. Walt & Bogdan Budnik
June 20, 2024
Nature Methods
Collaborative ethics: innovating collaboration between ethicists and life scientists

Jeantine E. Lunshof & Julia Rijssenbeek
June 7, 2024
Nature Computational Science
Scalable design of orthogonal DNA barcode libraries

Gokul Gowri, Kuanwei Sheng & Peng Yin
June 8, 2024
Tissue Engineering and Regenerative Medicine
Motion-Accommodating Dual-Layer Hydrogel Dressing to Deliver Adipose-Derived Stem Cells to Wounds

Jun Yong Lee, Jie Hyun Kim, Benjamin R. Freedman & David J. Mooney
June 10, 2024
Nature Biomedical Engineering
Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing

Smriti Pandey, Xin D. Gao, Nicholas A. Krasnow, Amber McElroy, Y. Allen Tao, Jordyn E. Duby, Benjamin J. Steinbeck, Julia McCreary, Sarah E. Pierce, Jakub Tolar, Torsten B. Meissner, Elliot L. Chaikof, Mark J. Osborn & David R. Liu
June 11, 2024
Nature
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank

Eliah G. Overbey, JangKeun Kim, Braden T. Tierney, Jiwoon Park, Nadia Houerbi, Alexander G. Lucaci, Sebastian Garcia Medina, Namita Damle, Deena Najjar, Kirill Grigorev, Evan E. Afshin, Krista A. Ryon, Karolina Sienkiewicz, Laura Patras, Remi Klotz, Veronica Ortiz, Matthew MacKay, Annalise Schweickart, Christopher R. Chin, Maria A. Sierra, Matias F. Valenzuela, Ezequiel Dantas, Theodore M. Nelson, Egle Cekanaviciute, Gabriel Deards, Jonathan Foox, S. Anand Narayanan, Caleb M. Schmidt, Michael A. Schmidt, Julian C. Schmidt, Sean Mullane, Seth Stravers Tigchelaar, Steven Levitte, Craig Westover, Chandrima Bhattacharya, Serena Lucotti, Jeremy Wain Hirschberg, Jacqueline Proszynski, Marissa Burke, Ashley Kleinman, Daniel J. Butler, Conor Loy, Omary Mzava, Joan Lenz, Doru Paul, Christopher Mozsary, Lauren M. Sanders, Lynn E. Taylor, Chintan O. Patel, Sharib A. Khan, Mir Suhail, Syed G. Byhaqui, Burhan Aslam, Aaron S. Gajadhar, Lucy Williamson, Purvi Tandel, Qiu Yang, Jessica Chu, Ryan W. Benz, Asim Siddiqui, Daniel Hornburg, Kelly Blease, Juan Moreno, Andrew Boddicker, Junhua Zhao, Bryan Lajoie, Ryan T. Scott, Rachel R. Gilbert, San-huei Lai Polo, Andrew Altomare, Semyon Kruglyak, Shawn Levy, Ishara Ariyapala, Joanne Beer, Bingqing Zhang, Briana M. Hudson, Aric Rininger, Sarah E. Church, Afshin Beheshti, George M. Church, Scott M. Smith, Brian E. Crucian, Sara R. Zwart, Irina Matei, David C. Lyden, Francine Garrett-Bakelman, Jan Krumsiek, Qiuying Chen, Dawson Miller, Joe Shuga, Stephen Williams, Corey Nemec, Guy Trudel, Martin Pelchat, Odette Laneuville, Iwijn De Vlaminck, Steven Gross, Kelly L. Bolton, Susan M. Bailey, Richard Granstein, David Furman, Ari M. Melnick, Sylvain V. Costes, Bader Shirah, Min Yu, Anil S. Menon, Jaime Mateus, Cem Meydan & Christopher E. Mason
June 10, 2024
Vaccine
Heterologous SARS-CoV-2 booster vaccine for individuals with hematological malignancies after a primary SARS-CoV-2 mRNA vaccine series

Amy C Sherman, Simon D van Haren, Ella Borberg, Zoe Swank, Muneerah Aleissa, Alexandra Tong, Rebecca Rooks, Urwah Kanwal, Hannah Levine, Bridget Yates, Natalie Izaguirre, Kevin Ryff, Sanya Thomas, Lindsey Parisi, Xiaofang Li, David R Walt, Ofer Levy, Stephen R Walsh, Nicolas C Issa, Lindsey R Baden
June 11, 2024
Nature Communications
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight

Jiwoon Park, Eliah G. Overbey, S. Anand Narayanan, JangKeun Kim, Braden T. Tierney, Namita Damle, Deena Najjar, Krista A. Ryon, Jacqueline Proszynski, Ashley Kleinman, Jeremy Wain Hirschberg, Matthew MacKay, Evan E. Afshin, Richard Granstein, Justin Gurvitch, Briana M. Hudson, Aric Rininger, Sean Mullane, Sarah E. Church, Cem Meydan, George Church, Afshin Beheshti, Jaime Mateus & Christopher E. Mason
June 11, 2024
Nature Microbiology
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight

Braden T. Tierney, JangKeun Kim, Eliah G. Overbey, Krista A. Ryon, Jonathan Foox, Maria A. Sierra, Chandrima Bhattacharya, Namita Damle, Deena Najjar, Jiwoon Park, J. Sebastian Garcia Medina, Nadia Houerbi, Cem Meydan, Jeremy Wain Hirschberg, Jake Qiu, Ashley S. Kleinman, Gabriel A. Al-Ghalith, Matthew MacKay, Evan E. Afshin, Raja Dhir, Joseph Borg, Christine Gatt, Nicholas Brereton, Benjamin P. Readhead, Semir Beyaz, Kasthuri J. Venkateswaran, Kelly Wiseman, Juan Moreno, Andrew M. Boddicker, Junhua Zhao, Bryan R. Lajoie, Ryan T. Scott, Andrew Altomare, Semyon Kruglyak, Shawn Levy, George M. Church & Christopher E. Mason
June 12, 2024
Journal of the American Chemical Society
Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin

Bibek Dhakal, Appi Mandhapati, Pradheep Eradi, Simon Park, Kirby Fibben, Kaicheng Li, Ashley DeYong, Samira Escopy, Geeta Karki, Diane D. Park, Carolyn A. Haller, Erbin Dai, Lijun Sun, Wilbur A. Lam, and Elliot L. Chaikof
June 12, 2024
Science Translational Medicine
Heterotypic immunity from prior SARS-CoV-2 infection but not COVID-19 vaccination associates with lower endemic coronavirus incidence

David J Bean, Janet Monroe, Yan Mei Liang, Ella Borberg, Yasmeen Senussi, Zoe Swank, Sujata Chalise, David Walt, Janice Weinberg, Manish Sagar