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178 Results for 'Microsystems'
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Technologies 10
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Paper-Based Diagnostics
With the imminent threat of new pandemics and frequent disease outbreaks exemplified by the recent Ebola and Zika epidemics, there is a growing need for low-cost, easily deployable and simple-to-use diagnostic tools. The Wyss Institute has developed paper-based synthetic gene networks as a next generation diagnostic technology for use in global healthcare crises and patient... -
Passive Directional Valve Technology: Towards More User-friendly and Accessible Microfluidic Devices for Diagnostic and Research Applications
Passive directional valves enable smaller and more complex microfluidics applications across of broad spectrum of future technologies, including diagnostics, drug development, and tissue engineering. -
FcMBL: Broad-Spectrum Pathogen Capture for Infectious Disease Diagnosis and Therapy
The Problem Infectious diseases have plagued humanity for millennia, and the pathogens that infect and sicken humans are constantly evolving. Severe infections can cause sepsis, a life-threatening condition in which a patient’s immune system overreacts to the infection. The body starts to attack itself, which can lead to tissue damage, organ failure, and death. Sepsis... -
milliDelta: Millimeter-Scale Delta Robot
Delta robots are deployed in many industrial processes, including pick-and-place assemblies, machining, welding, and food packaging. Three individually controlled lightweight arms enable fast and accurate motion of an output platform in three directions. Roboticists have reduced the size of Delta robots for tasks in limited workspaces, but so far, using conventional manufacturing techniques and components,... -
HAMR: Versatile Crawling Microrobot
Small or difficult-to-access spaces such as areas covered with rubble, or narrow pipes and engines can pose obstacles to search-and-rescue missions, repair works, or environmental and industrial monitoring. One solution for these problems could be small-sized robots that are able to navigate such spaces, transport payload, sense, and communicate. Wyss Institute researchers have developed a... -
Microfluidic Hemostasis Monitor
The body’s ability to stop bleeding, also known as hemostasis, is critical for survival. For patients with blood clotting disorders, medical conditions requiring the use of anticoagulation or antiplatelet drugs, or who require treatment with extracorporeal devices that circulate their blood outside of the body, it is essential that care providers can rapidly monitor their...
News 121
Multimedia 47
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Video/AnimationMice Don’t Menstruate: Reimagining Women’s Health Using Organ Chips with Dr. Donald IngberIn this episode, host Sharon Kedar, Co-Founder of Northpond Ventures, is joined by Dr. Donald Ingber, Founding Director at Wyss Institute for Biologically Inspired Engineering at Harvard University. Dr. Ingber’s commitment to following his passion has led him to countless medical and technological breakthroughs, including Organ Chip technology. These incredible chips recreate the structure and...
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Video/AnimationBridging science, engineering, and art: from mechanobiology to Human Organs-on-ChipsIn this Marsilius Lecture, Wyss Founding Director Don Ingber shares his personal path from a serendipitous experience in an undergraduate art class that led to his discovery of how living cells are constructed using “tensegrity” architecture and how this contributed to the birth of the field of Mechanobiology to his more recent work on human...
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Video/AnimationHow do we make safer and more effective drugs?Wyss researchers are using an ever-growing number of human tissue-mimicking Organ Chips to improve and accelerate the drug development process for a wide number of unmet diseases – and understand what causes them to erupt. More recently, they added a human Vagina Chip and personalized Barrett’s esophagus Chip to their arsenal, and created in vitro...
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Video/AnimationWyss Institute Brain Targeting ProgramThis animation explains how Wyss Institute researchers and their industry partners aim to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain. Credit: Wyss Institute at Harvard University.
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Video/AnimationInterrogator: Human Organ-on-ChipsThis video describes the “Interrogator” instrument that can be programmed to culture up to 10 different Organ Chips and sequentially transfer fluids between their vascular channels to mimic normal human blood flow between the different organs of our body. Its integrated microscope enables the continuous monitoring of the tissues’ integrities in the individual organ chips...
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Video/AnimationMORPH: A new soft material microfabrication processWhat has the ability to move and show its colors, is made only of silicone rubber and manufactured at the millimeter scale? A soft robotic peacock spider. Researchers have combined three different manufacturing techniques to create a novel origami-inspired soft material microfabrication process that goes beyond what existing approaches can achieve at this small scale....