Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

November 29, 2024
Cells
Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer’s Disease and Autoimmune Diseases

Jonathan Sundstrom, Emma Vanderleeden, Nathaniel J Barton, Sambra D Redick, Pepper Dawes, Liam F Murray, Meagan N Olson, Khanh Tran, Samantha M Chigas, Adrian R Orszulak, George M Church, Benjamin Readhead, Hyung Suk Oh, David M Harlan, David M Knipe, Jennifer P Wang, Yingleong Chan, Elaine T Lim
December 9, 2024
Small Methods
Cargo Quantification of Functionalized DNA Origami for Therapeutic Application

Olivia J. Young, Hawa Dembele, Anjali Rajwar, Ick Chan Kwon, Ju Hee Ryu, William M. Shih, Yang C. Zeng
December 9, 2024
Nature Biotechnology
Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells

Esha Madan, António M. Palma, Vignesh Vudatha, Amit Kumar, Praveen Bhoopathi, Jochen Wilhelm, Tytus Bernas, Patrick C. Martin, Gaurav Bilolikar, Aenya Gogna, Maria Leonor Peixoto, Isabelle Dreier, Thais Fenz Araujo, Elena Garre, Anna Gustafsson, Kalpana Deepa Priya Dorayappan, Narsimha Mamidi, Zhaoyu Sun, Michail Yekelchyk, Davide Accardi, Amalie Lykke Olsen, Lin Lin, Asaf Ashkenazy Titelman, Michael Bianchi, Phil Jessmon, Elnaz Abbasi Farid, Anjan K. Pradhan, Lena Neufeld, Eilam Yeini, Santanu Maji, Christopher J. Pelham, Hyobin Kim, Daniel Oh, Hans Olav Rolfsnes, Rita C. Marques, Amy Lu, Masaki Nagane, Sahil Chaudhary, Kartik Gupta, Keshav C. Gogna, Ana Bigio, Karthikeya Bhoopathi, Padmanabhan Mannangatti, K. Gopinath Achary, Javed Akhtar, Sara Belião, Swadesh Das, Isabel Correia, Cláudia L. da Silva, Arsénio M. Fialho, Michael J. Poellmann, Kaila Javius-Jones, Adam M. Hawkridge, Sanya Pal, Kumari S. Shree, Emad A. Rakha, Sambhav Khurana, Gaoping Xiao, Dongyu Zhang, Arjun Rijal, Charles Lyons, Steven R. Grossman, David P. Turner, Raghavendra Pillappa, Karanvir Prakash, Gaurav Gupta, Gary L. W. G. Robinson, Jennifer Koblinski, Hongjun Wang, Gita Singh, Sujay Singh, Sagar Rayamajhi, Manny D. Bacolod, Hope Richards, Sadia Sayeed, Katherine P. Klein, David Chelmow, Ronit Satchi-Fainaro, Karuppaiyah Selvendiran, Denise Connolly, Frits Alan Thorsen, Rolf Bjerkvig, Kenneth P. Nephew, Michael O. Idowu, Mark P. Kühnel, Christopher Moskaluk, Seungpyo Hong, William L. Redmond, Göran Landberg, Antonio Lopez-Beltran, Andrew S. Poklepovic, Arun Sanyal, Paul B. Fisher, George M. Church, Usha Menon, Ronny Drapkin, Andrew K. Godwin, Yonglun Luo, Maximilian Ackermann, Alexandar Tzankov, Kirsten D. Mertz, Danny Jonigk, Allan Tsung, David Sidransky, Jose Trevino, Arturo P. Saavedra, Robert Winn, Kyoung Jae Won, Eduardo Moreno & Rajan Gogna
December 9, 2024
Nature Protocols
An explainable deep learning platform for molecular discovery

Felix Wong, Satotaka Omori, Alicia Li, Aarti Krishnan, Ryan S. Lach, Joseph Rufo, Maxwell Z. Wilson & James J. Collins
December 11, 2024
Nature
Sacrificial capillary pumps to engineer multiscalar biological forms

Subramanian Sundaram, Joshua H. Lee, Isabel M. Bjørge, Christos Michas, Sudong Kim, Alex Lammers, João F. Mano, Jeroen Eyckmans, Alice E. White & Christopher S. Chen
December 2, 2024
Bioessays
The Multiscale Wisdom of the Body: Collective Intelligence as a Tractable Interface for Next-Generation Biomedicine

Michael Levin
November 22, 2024
Journal of Controlled Release
Backpack-carrying macrophage immunotherapy for periodontitis

Mayuka Nakajima, Neha Kapate, John R Clegg, Mayumi Ikeda-Imafuku, Kyung Soo Park, Ninad Kumbhojkar, Vinny Chandran Suja, Supriya Prakash, Lily Li-Wen Wang, Koichi Tabeta, Samir Mitragotri
November 21, 2024
Nature Methods
Accurate RNA 3D structure prediction using a language model-based deep learning approach

Tao Shen, Zhihang Hu, Siqi Sun, Di Liu, Felix Wong, Jiuming Wang, Jiayang Chen, Yixuan Wang, Liang Hong, Jin Xiao, Liangzhen Zheng, Tejas Krishnamoorthi, Irwin King, Sheng Wang, Peng Yin, James J. Collins & Yu Li
May 4, 2024
Bioengineering & Translational Medicine
Antibody drug conjugates in the clinic

Edidiong Udofa, Disha Sankholkar, Samir Mitragotri, Zongmin Zhao
May 16, 2024
Bioengineering & Translational Medicine
Hydrogels in the clinic: An update

John R. Clegg, Kolade Adebowale, Zongmin Zhao, Samir Mitragotri
May 1, 2024
Bioengineering & Translational Medicine
Hemostats in the clinic

Maithili Joshi, Zongmin Zhao, Samir Mitragotri
October 2, 2024
Matter
Stiff Hydrogel Encapsulation Retains Mesenchymal Stem Cell Stemness for Regenerative Medicine

Bo Li, Liyuan Zhang, Yuan Yin, Anqi Chen, Bo Ri Seo, Junzhe Lou, David J Mooney, David A Weitz
November 18, 2024
PNAS
IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines

Miguel C. Sobral, Laura Cabizzosu, Shawn J. Kang, Kyle Ruark, Alex J. Najibi, Ryan S. Lane, Einat Vitner, Hamza Ijaz, Maxence O. Dellacherie, Mason T. Dacus, Christina M. Tringides, Irene de Lázaro, Mikaël J. Pittet, Sören Müller, Shannon J. Turley, and David J. Mooney
November 18, 2024
Advanced Science
Matrix Architecture and Mechanics Regulate Myofibril Organization, Costamere Assembly, and Contractility in Engineered Myocardial Microtissues

Samuel J. DePalma, Javiera Jilberto, Austin E. Stis, Darcy D. Huang, Jason Lo, Christopher D. Davidson, Aamilah Chowdhury, Robert N. Kent III, Maggie E. Jewett, Hiba Kobeissi, Christopher S. Chen, Emma Lejeune, Adam S. Helms, David A. Nordsletten, Brendon M. Baker
November 11, 2024
Scientific Reports
Multicellular adaptation to electrophysiological perturbations analyzed by deterministic and stochastic bioelectrical models

Javier Cervera, Michael Levin & Salvador Mafe
October 7, 2024
Open Forum Infectious Diseases
Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission During the Omicron Era in Massachusetts: A Prospective, Case-Ascertained Study Using Genomic Epidemiology

Jaspreet Banga, Taylor Brock-Fisher, Brittany A Petros, Eric Y Dai, Ariana T Leonelli, Sabrina T Dobbins, Katelyn S Messer, Audrey B Nathanson, Amelia Capone, Nancy Littlehale, Viola Appiah-Danquah, Siang Dim, Gage K Moreno, Maura Crowther, Katherine C DeRuff, Bronwyn L MacInnis, Michael Springer, Pardis C Sabeti, Kathryn E Stephenson
November 12, 2024
Biomaterials Science
Photoinitiator-free light-mediated crosslinking of dynamic polymer and pristine protein networks

Riccardo Rizzo, Dylan M Barber, Jackson K Wilt, Alexander J Ainscough, Jennifer A Lewis
November 8, 2024
Science Advances
A coronaviral pore-replicase complex links RNA synthesis and export from double-membrane vesicles

Anan Chen, Ana-Mihaela Lupan, Rui Tong Quek, Stefan G Stanciu, Mihaela Asaftei, George A Stanciu, Kierra S Hardy, Taciani de Almeida Magalhães, Pamela A Silver, Timothy J Mitchison, Adrian Salic
November 8, 2024
Nature Methods
Induced pluripotent stem cell-derived cardiomyocyte in vitro models: benchmarking progress and ongoing challenges

Jourdan K. Ewoldt, Samuel J. DePalma, Maggie E. Jewett, M. Çağatay Karakan, Yih-Mei Lin, Paria Mir Hashemian, Xining Gao, Lihua Lou, Micheal A. McLellan, Jonathan Tabares, Marshall Ma, Adriana C. Salazar Coariti, Jin He, Kimani C. Toussaint Jr., Thomas G. Bifano, Sharan Ramaswamy, Alice E. White, Arvind Agarwal, Emma Lejeune, Brendon M. Baker & Christopher S. Chen
October 23, 2024
10th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob)
Deep-Learning Based Lumbar Moment Estimation During Exosuit Augmented Lifting with Variable Loading Conditions

Philipp Arens; D. Adam Quirk; Conor J. Walsh