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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

January 17, 2025
ALTEX
Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare

Uwe Marx , Sonja Beken, Zaozao Chen, Eva-Maria Dehne, Ann Doherty, Lorna Ewart, Suzanne C. Fitzpatrick, Linda G. Griffith, Zhongze Gu, Thomas Hartung, James Hickman, Donald E. Ingber, Seiichi Ishida, Jayoung Jeong, Marcel Leist, Lisa Levin, Donna L. Mendrick, Giorgia Pallocca, Stefan Platz, Marian Raschke, Lena Smirnova, Danilo A. Tagle, Martin Trapecar, Bas W. M. van Balkom, Janny van den Eijnden-van Raaij, Andries van der Meer, Adrian Roth
April 11, 2025
Cancer Immunology Research
First-in-Human Clinical Trial of Vaccination with WDVAX, a Dendritic Cell Activating Scaffold Incorporating Autologous Tumor Cell Lysate, in Metastatic Melanoma Patients

F Stephen Hodi, Anita Giobbie-Hurder, Kwasi Adu-Berchie, Srin Ranasinghe, Ana Lako, Mariano Severgnini, Emily M Thrash, Jason L Weirather, Joanna Baginska, Michael P Manos, Edward J Doherty, Alexander Stafford, Heather Daley, Jerome Ritz, Patrick A Ott, Kathleen L Pfaff, Scott J Rodig, Charles H Yoon, Glenn Dranoff, David J Mooney
April 11, 2025
Nature Communications
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates

Nadia A. Erkamp, Mina Farag, Yuanxin Qiu, Daoyuan Qian, Tomas Sneideris, Tingting Wu, Timothy J. Welsh, Hannes Ausserwöger, Tommy J. Krug, Gaurav Chauhan, David A. Weitz, Matthew D. Lew, Tuomas P. J. Knowles & Rohit V. Pappu
April 5, 2025
Bio-Protocol Journal
A Human Cervix Chip for Preclinical Studies of Female Reproductive Biology

Zohreh Izadifar, Donald E Ingber
April 14, 2025
PLOS Computational Biology
Revealing non-trivial information structures in aneural biological tissues via functional connectivity

Douglas Blackiston, Hannah Dromiack, Caitlin Grasso, Thomas F Varley, Douglas G Moore, Krishna Kannan Srinivasan, Olaf Sporns, Joshua Bongard, Michael Levin, Sara I Walker
April 16, 2025
Nature Communications
Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy

Daisuke Yoshinaga, Isabel Craven, Rui Feng, Maksymilian Prondzynski, Kevin Shani, Yashasvi Tharani, Joshua Mayourian, Milosh Joseph, David Walker, Raul H. Bortolin, Chrystalle Katte Carreon, Bridget Boss, Sheila Upton, Kevin Kit Parker, William T. Pu & Vassilios J. Bezzerides
April 8, 2025
Journal of the American Chemical Society
High-Throughput Extracellular Vesicle Isolation Using Plate-Based Size Exclusion Chromatography and Automation

Tal Gilboa, Dmitry Ter-Ovanesyan, Clarissa May Babila, Sara Whiteman, Shad Morton, David Kalish, Jamie Johnston, David Tesin, Matthew Davies, Jenny M. Tam, George M. Church, David R. Walt
April 9, 2025
Science Advances
Preference-based assistance optimization for lifting and lowering with a soft back exosuit

Philipp Arens, D Adam Quirk, Weiwei Pan, Yaniv Yacoby, Finale Doshi-Velez, Conor J Walsh
March 12, 2025
International Journal of Molecular Sciences
Host Serine Proteases and Antiviral Innate Immunity as Potential Therapeutic Targets in Influenza A Virus Infection-Induced COPD Exacerbations

Haiqing Bai, Melissa Rodas, Longlong Si, Yuncheng Man, Jie Ji, Roberto Plebani, Johnathan D Mercer, Rani K Powers, Chaitra Belgur, Amanda Jiang, Sean R R Hall, Rachelle Prantil-Baun, Donald E Ingber
March 26, 2025
ACS Applied Materials & Interfaces
Electrical Impedance Correlated to Flow Rate in Elastomeric Valves: An Analog Material Memory

Joel Dungan, Juanita Mathews, Jeffrey T. Borenstein, Michael Levin, Valencia Koomson
March 13, 2025
ACS Synthetic Biology
XanthoMoClo─A Robust Modular Cloning Genetic Toolkit for the Genera Xanthobacter and Roseixanthobacter

Maximillian P. M. Soltysiak, Audrey L. H. Ory, Andrew D. Lee, Caroline E. Christophersen, Amogh P. Jalihal, Michael Springer
March 17, 2025
Journal of Extracellular Vesicles
Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays

Maia Norman, Adnan Shami-shah, Sydney C. D'Amaddio, Benjamin G. Travis, Dmitry Ter-Ovanesyan, Tyler J. Dougan, David R. Walt
March 6, 2025
NPJ Precision Oncology
LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker

Pamela R. de Santiago, Sho Sato, Stephanie J. Zhang, Meaghan C. Dougher, Kyle M. Devins, Agnes J. Bilecz, Sagar Rayamajhi, Gabriel Mingo, Hannah S. Rendulich, Yi Feng, Connie Wu, Martin S. Taylor, Yelena Zhuravlev, Euihye Jung, Dalia K. Omran, Tian-Li Wang, Ie-Ming Shih, Lauren E. Schwartz, Sarah Kim, Mark A. Morgan, Janos L. Tanyi, Kathleen H. Burns, Ernst Lengyel, Carlos Parra-Herran, Andrew K. Godwin, David R. Walt & Ronny Drapkin
March 6, 2025
biosensors
An Antimicrobial and Antifibrotic Coating for Implantable Biosensors

Sofia Wareham-Mathiassen, Pawan Jolly, Nandhinee Radha Shanmuga, Badrinath Jagannath, Pranav Prabhala, Yunhao Zhai, Alican Ozkan, Arash Naziripour, Rohini Singh, Henrik Bengtsson,Thomas Bjarnsholt, and Donald E. Ingber
February 24, 2025
Nature Protocols
Circular Vectors as an efficient, fully synthetic, cell-free approach for preparing small circular DNA as a plasmid substitute for guide RNA expression in CRISPR–Cas9 genome editing

Roman Teo Oliynyk & George M. Church
March 3, 2025
PNAS
Vimentin undergoes liquid-liquid phase separation to form droplets which wet and stabilize actin fibers

Arkaprabha Basu, Tommy Krug, Benjamin du Pont, Qiaoling Huang, Sijie Sun, Stephen A Adam, Robert D Goldman, David A Weitz
February 17, 2025
Communicative & Integrative Biology
Life, its origin, and its distribution: a perspective from the Conway-Kochen Theorem and the Free Energy Principle

Chris Fields, Michael Levin
February 1, 2025
Review of Scientific Instruments
A microfluidic sucrose gap device for electrical measurement of gap junction connectivity

J Dungan, J Mathews, M Levin, V Koomson
January 31, 2025
Science
Randomizing the human genome by engineering recombination between repeat elements

Jonas Koeppel, Raphael Ferreira, Thomas Vanderstichele, Lisa Maria Riedmayr, Elin Madli Peets, Gareth Girling, Juliane Weller, Pierre Murat, Fabio Giuseppe Liberante, Tom Ellis, George McDonald Church, Leopold Parts
January 31, 2025
Journal of Control Release
Immobilization of BMP-2 in porous hydrogels to spatially regulate osteogenesis

Junzhe Lou, Charlotte Meyer, Anqi Chen, David A Weitz, David J Mooney