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Conceptual photo of pregnancy healthcare. Closeup photo of medicines on table next to pregnant woman

Stroma Tx: Safe Pregnancy for IBD Patients

Understanding the connections between IBD and pregnancy

Join us as we reimagine women’s health

We’re seeking passionate supporters to help advance our groundbreaking research.

Project Stage

Pre-Validation

Team
Don Ingber Alican Ozkan Girija Goyal Karina Calderon Nina LoGrande

Patients with Inflammatory Bowel Disease (IBD) are advised to achieve remission before pregnancy, in an effort to decrease pregnancy-related intestinal issues, including fibrosis. Yet the exact mechanisms underlying the fluctuation of their symptoms remain unclear and there are no treatments currently available. To close this knowledge gap, we are treating our IBD Organ Chips with pregnancy-related hormones to mimic changes in intestinal inflammation and aid in future drug discoveries to support safer pregnancies.

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