125 Results for 'Physiology'
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CircaVent: A Drug Discovery Platform for Mental Health Conditions
CircaVent is a novel drug discovery platform that combines predictive algorithms, high-throughput preclinical models, and human organoids to identify and test drugs that could treat mental health conditions like bipolar disorder.
Soft Robotic Glove for Neuromuscular Rehabilitation
The soft robotic glove helps restore lost hand function in patients with neurological conditions using inflatable chambers that gently bend and straighten the fingers repeatedly. Wyss startup Imago Rehab launched in 2021 to commercialize this technology for at-home rehabilitation of stroke survivors, and aims to expand its offerings into other areas of rehabilitation.
FcMBL: Broad-Spectrum Pathogen Capture for Infectious Disease Diagnosis and Therapy
The Problem Infectious diseases have plagued humanity for millennia, and the pathogens that infect and sicken humans are constantly evolving. Severe infections can cause sepsis, a life-threatening condition in which a patient’s immune system overreacts to the infection. The body starts to attack itself, which can lead to tissue damage, organ failure, and death. Sepsis...
FitBiomics is commercializing probiotic supplements based on unique combinations of microbes found in elite athletes’ guts to help optimize the health and function of all humans.
Soft Robotic Shoulder Support for Stroke Rehabilitation
The majority of stroke survivors have difficulty using their affected arm in everyday life. Commercial rehabilitation robots exist, but most are expensive, rigid, non-portable exoskeletons that can only be used in clinical rehabilitation settings. Portable devices could considerably increase the frequency and amount of robotic therapy, maximizing the recovery possible for patients with arm impairments....
JetValve for Heart Regeneration
The human heart beats approximately 35 million times every year, pumping blood into the circulation via four different heart valves. In more than four million people each year, heart valves fail for different reasons, including birth defects, age-related deteriorations and infections. At present, clinicians use either artificial prostheses or fixed animal and cadaver-sourced tissue to...
Video/AnimationInterrogator: Human Organ-on-ChipsThis video describes the “Interrogator” instrument that can be programmed to culture up to 10 different Organ Chips and sequentially transfer fluids between their vascular channels to mimic normal human blood flow between the different organs of our body. Its integrated microscope enables the continuous monitoring of the tissues’ integrities in the individual organ chips...
Video/AnimationHip-only Soft Exosuit for both Walking and RunningThis video demonstrates the use of the hip-assisting exosuit in different natural environments, and shows how the robotic device senses changes in the gait-specific vertical movements of the center of mass during walking and running to rapidly adjust its actuation. Credit: Wyss Institute at Harvard University
Video/AnimationMulti-joint Personalized Soft Exosuit Breaks New GroundA multidisciplinary team at Harvard’s Wyss Institute and Harvard SEAS has developed a mobile multi-joint soft exosuit using an automatic tuning strategy that could reduce fatigue in soldiers, firefighters or other rescue workers. Credit: Wyss Institute at Harvard University
Video/AnimationSoft Exosuit: Human-in-the-Loop Bayesian OptimizationResearchers from the Wyss Institute and Harvard SEAS have developed a human-in-the-loop Bayesian optimization method to personalize the hip assistance that a soft exosuit can provide. The optimized assistance helps reduce metabolic cost compared to walking without the device, or with the device not further personalized. Credit: Harvard Biodesign Lab/Harvard Agile Robotics Lab Learn more...
Video/AnimationNew Wyss Institute Initiative – 3D Organ EngineeringWyss Institute Core Faculty members Christopher Chen and Jennifer Lewis describe the Wyss Institute’s new initiative focused on organ engineering, which leverages our expertise in biomaterials, tissue engineering, three dimensional biofabrication, and stem cell development.
Audio/PodcastFormer DI Hoopster Searches For Athletic Boost In The MicrobiomeFormer DI Hoopster Searches For Athletic Boost In The Microbiome was originally broadcast on WBUR’s Only a Game on August 4, 2017. The story features Wyss Core Faculty member George Church and Postdoctoral Fellow Jonathan Scheiman. The original broadcast story can be found here.