Technologies search results
14 Results for ''
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Engineered Live Biotherapeutic Product (eLBP) to Protect the Microbiome from Antibiotics
eLBP is a safe and cost-effective therapeutic for patients treated with beta-lactam antibiotics that safeguards against the loss of health-essential microbes while preventing the development and spread of antibiotic resistance. -
Ichor: Reversing Aging
Ichor is addressing multiple age-related diseases by identifying genetic interventions that reprogram old cells to a younger state. Therapies based on these interventions could improve survival for cancer patients and long-term cardiovascular and neurological health. -
ReConstruct: Vascularized tissue for breast reconstruction and augmentation
ReConstruct is a platform for growing, vascularizing, and implanting patient-derived tissues that enable safer breast reconstruction after cancer surgery. -
Sustained Growth Factor Delivery for Regenerating Tissues
The Problem Millions of people worldwide suffer from traumatic injuries or health conditions that cause damage to soft tissues including nerves, muscles, and blood vessels. The body can heal some of that damage, but more serious cases like the severing of a nerve or sustained oxygen deprivation can lead to permanent loss of movement or... -
Kidney Engineering Technology for New Tissue Replacement Therapies
Trestle Biotherapeutics licensed 3D bioprinting, and stem cell and kidney organoid engineering methods to help it create kidney repair and replacement therapies. These could become new standard-of-care options beyond dialysis and kidney transplants for patients with kidney failure. -
PhonoGraftTM: Biomimetic Hearing-restoration Technology
PhonoGraft is an eardrum-regenerating device that enables better and longer-lasting eardrum reconstruction, reducing the need for invasive surgeries and minimizing the risk of long-term hearing loss. Wyss startup Beacon Bio was acquired by Desktop Health, a healthcare business within Desktop Metal, Inc. which is further developing this technology towards commercialization with the former Wyss startup team leading the way. -
MRBL: Next-Generation Gene Therapy for Molecular Skin Rejuvenation
The next-generation gene therapy for molecular skin rejuvenation combines a comprehensive target gene prediction with a novel transdermal delivery approach for therapeutic adenovirus-associated viruses. The platform targets monogenic disease indications in the skin, and extends the same targets to the treatment of common skin aging conditions. -
Bone Marrow-Like Scaffolds for Accelerating Immune Reconstitution
An implantable bone marrow cryogel to accelerate the full reconstitution of the immune system, including T cell immunity, in patients that received chemotherapy and a bone marrow transplant. This could provide an off-the-shelf, material-based solution for patients with severe blood disorders whose immunity is recovering only slowly after treatment. -
Soft Robotic Shoulder Support for Stroke Rehabilitation
The majority of stroke survivors have difficulty using their affected arm in everyday life. Commercial rehabilitation robots exist, but most are expensive, rigid, non-portable exoskeletons that can only be used in clinical rehabilitation settings. Portable devices could considerably increase the frequency and amount of robotic therapy, maximizing the recovery possible for patients with arm impairments.... -
Engineered Brain Organoids
The ability to derive and manipulate pluripotent stem cells has opened up new avenues for modeling biological systems in both healthy and diseased conditions. In order to more fully recapitulate the tissue microenvironment with its cell-cell, cell-extracellular matrix, and cell-niche interactions, it is essential to transition stem-cell culturing from monolayers to 3D structures. Self-organization of... -
Focused Rotary Jet Spinning for Heart Implants
Focused rotary jet spinning (FRJS) is a manufacturing technique that can rapidly spin polymers into long fibers that are easily shaped into heart valves for treating a variety of cardiac diseases in children and adults. -
Targeted EPO: Safely Normalizing Oxygen Delivery in a Broad Range of Disease Conditions
General Biologics commercializes Targeted EPO as a first-in-class fusion protein therapeutic for the treatment of life-threatening and limiting hypoxia in various disease conditions, including COPD, cystic fibrosis, COVID-19, and severe anemias, such as in patients with kidney failure. -
Injectable Hydrogels for Better Drug Delivery
Wyss researchers have developed a new approach to delivering drugs and therapeutic cells using biocompatible and biodegradable hydrogels made of alginate, a naturally occurring polysaccharide from brown algae. Injectable hydrogels could greatly improve clinical ability to provide extended drug release and controlled delivery throughout the body or at targeted local sites. The method holds promising... -
3D Bioprinting of Living Tissues
The Problem There is a severe shortage of human organs for people who need transplants due to injury or disease: more than 103,000 people are on the waiting list for organs in the US, and it’s estimated that 17 people die waiting for an organ transplant every day. Growing full organs from living human...