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106 Results for 'James J. Collins'
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Technologies 6
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Using Systems Biology to Find and Test New Drugs Faster
The pharmaceutical industry is infamous for big numbers: it takes 10-15 years and can cost over $2 billion to bring a new drug from the lab to the market. Up to 6 of those years and $1 billion are spent in laborious preclinical trials to identify and validate new potential drug compounds, and much of... -
INSPECTR™: Direct-to-Consumer Molecular Diagnostic
Molecular diagnostics is the fastest growing segment of the global in vitro diagnostics market. There remains a gap, however, in providing this technology directly to consumers in a format that is as cost effective and as simple to use as a lateral flow immunoassay, like glucose and pregnancy tests. Scientists at the Wyss Institute have... -
Cell-Free Biomolecule Manufacturing
Wyss Institute researchers have developed a biomolecular manufacturing method that can quickly and easily produce a wide range of vaccines, antimicrobial peptides and antibody conjugates while doing so anywhere, even in places without access to electrical power or refrigeration. The breakthrough could provide a life-saving workaround for making modern interventions available in remote areas. Today... -
Vibrating Insoles for Better Balance
Balance in humans relies on complex feedback from the senses that govern the body’s mechanical stability. Wyss Institute and Boston University researchers have discovered that random vibrations, too gentle to be felt, can improve the sensory feedback system and may restore stability through a mechanism known as “stochastic resonance”. By incorporating vibrating elements in insoles... -
Active Mattress for Infant Health
Clinicians and engineers at the Wyss Institute and the University of Massachusetts Medical School have developed a unique and proprietary system that reduces the onset of neonatal apnea in low birth-weight infants in a clinical trial at Beth Israel Deaconess Medical Center. The system makes use of the concept of Stochastic Resonance to reset the... -
Paper-Based Diagnostics
With the imminent threat of new pandemics and frequent disease outbreaks exemplified by the recent Ebola and Zika epidemics, there is a growing need for low-cost, easily deployable and simple-to-use diagnostic tools. The Wyss Institute has developed paper-based synthetic gene networks as a next generation diagnostic technology for use in global healthcare crises and patient...
News 79
Events 9
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Sep 20, 2019, 8:20am - 6:00pmWyss Event
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The 10th International Wyss Institute Symposium will focus on Next-Generation Diagnostics; convening the Institute’s vast network of collaborators, students, researchers, faculty and clinicians alongside industrial researchers, and members of academic institutions and foundations leading the development of diagnostics technology. This year’s Symposium will highlight the latest developments of this emerging field and address the need... Free and open to public -
Jun 3, 2019, 1:00pm - 2:00pmLecture
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Wyss Core Faculty member James J. Collins will be speaking at a Brigham and Women’s Pathology Grand Rounds event on Monday, June 3 from 1 PM to 2 PM. The topic is, “Point of care diagnostics based on synthetic biology.” Accreditation Partners HealthCare System is accredited by the Accreditation Council for Continuing Medical Education... Free and open to public -
Feb 26, 2019, 1:00pm - 2:00pmLecture
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On Tuesday, February 26, join Brigham and Women’s Hospital for the weekly Clinical Pathology Conference lecture series featuring Wyss Core Faculty member James Collins. James Collins is a founder of the field of synthetic biology and a pioneer in the application of systems biology concepts to solve major biomedical problems. His internationally acclaimed research uses network... Free and open to public
Multimedia 12
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Video/AnimationUsing deep learning to detect cancerous skin lesionsMelanoma is a very severe cancer that is often diagnosed too late to save patients’ lives, and most people do not regularly visit a dermatologist for skin exams. Early-stage identification of suspicious pigmented lesions (SPLs), ideally by primary care providers, could lead to improved melanoma prognosis. Researchers at the Wyss Institute and MIT have developed... -
Audio/PodcastLab Notes #1 | A wearable diagnostic for COVID-19The Allen Institute is dedicated to answering some of the biggest questions in bioscience and accelerating research worldwide. They are a recognized leader in large-scale research with a commitment to openly sharing their data, tools and knowledge with scientists around the world. In the first episode of their podcast Lab Notes, they interview Wyss Core... -
Audio/PodcastFrom the Old Chemistry Set to the New ‘BioBits,’ Cutting-Edge Kit to Teach BiologyFrom the Old Chemistry Set to the New ‘BioBits,’ Cutting-Edge Kit to Teach Biology was originally broadcast on WBUR on November 23, 2018. This story features Wyss Core Faculty member James Collins. The original broadcast story can be found here. -
Video/AnimationBioBitsResearchers at the Wyss Institute, MIT, and Northwestern University have collaborated to create “BioBits,” a low-cost, shelf-stable educational kit to teach synthetic and molecular biology in K-12 classrooms. The kit utilizes freeze-dried cell-free reactions that eliminate the need for growing living cells in order to perform biological experiments. Different modules in the kit teach students... -
Audio/PodcastDisruptive: Rapid, Low-Cost Detection of Zika & Future PandemicsThe rapid emergence of the Zika virus on the world stage calls for a detection system that is just as quick. In this episode of Disruptive, Wyss Core Faculty member and MIT professor Jim Collins and University of Toronto Assistant Professor Keith Pardee discuss how they developed a low cost, paper-based diagnostic platform that can... -
Video/AnimationDetecting Zika: A platform for rapid, low-cost diagnosticsIn this video, a team of collaborators led by Wyss Core Faculty member James Collins discuss a low-cost, paper-based diagnostic system that they developed for detecting specific strains of the Zika virus, with the goal that it could soon be used in the field to easily screen blood, urine, or saliva samples. Credit: Wyss Institute...