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113 Results for 'James J. Collins'
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Technologies 7
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wFDCF Face Masks: A Wearable COVID-19 Diagnostic
The Problem The COVID-19 pandemic has made it starkly clear that the world lacks rapid, accurate diagnostic tests for pathogens. When patients arrive in a medical facility for treatment, the triage process is hindered by diagnostic tests that are inaccurate or take a long time to produce results. In addition, patients who are asymptomatic and... -
Using Systems Biology to Find and Test New Drugs Faster
The pharmaceutical industry is infamous for big numbers: it takes 10-15 years and can cost over $2 billion to bring a new drug from the lab to the market. Up to 6 of those years and $1 billion are spent in laborious preclinical trials to identify and validate new potential drug compounds, and much of... -
INSPECTR™: Direct-to-Consumer Molecular Diagnostic
INSPECTR™ is a molecular diagnostic platform that combines freeze-dried synthetic gene networks with cell-free expression systems to create novel biosensors that detect and report the presence of a target DNA or RNA molecule without the need for power or lab equipment. This technology was licensed by Wyss startup Sherlock Biosciences in 2019. -
Cell-Free Biomolecule Manufacturing
Wyss Institute researchers have developed a biomolecular manufacturing method that can quickly and easily produce a wide range of vaccines, antimicrobial peptides and antibody conjugates while doing so anywhere, even in places without access to electrical power or refrigeration. The breakthrough could provide a life-saving workaround for making modern interventions available in remote areas. Today... -
Vibrating Insoles for Better Balance
Balance in humans relies on complex feedback from the senses that govern the body’s mechanical stability. Wyss Institute and Boston University researchers have discovered that random vibrations, too gentle to be felt, can improve the sensory feedback system and may restore stability through a mechanism known as “stochastic resonance”. By incorporating vibrating elements in insoles... -
Active Mattress for Infant Health
Clinicians and engineers at the Wyss Institute and the University of Massachusetts Medical School have developed a unique and proprietary system that reduces the onset of neonatal apnea in low birth-weight infants in a clinical trial at Beth Israel Deaconess Medical Center. The system makes use of the concept of Stochastic Resonance to reset the...
News 81
Events 9
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Sep 20, 2019, 8:20am - 6:00pmWyss Event
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The 10th International Wyss Institute Symposium will focus on Next-Generation Diagnostics; convening the Institute’s vast network of collaborators, students, researchers, faculty and clinicians alongside industrial researchers, and members of academic institutions and foundations leading the development of diagnostics technology. This year’s Symposium will highlight the latest developments of this emerging field and address the need... Free and open to public -
Jun 3, 2019, 1:00pm - 2:00pmLecture
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Wyss Core Faculty member James J. Collins will be speaking at a Brigham and Women’s Pathology Grand Rounds event on Monday, June 3 from 1 PM to 2 PM. The topic is, “Point of care diagnostics based on synthetic biology.” Accreditation Partners HealthCare System is accredited by the Accreditation Council for Continuing Medical Education... Free and open to public -
Feb 26, 2019, 1:00pm - 2:00pmLecture
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On Tuesday, February 26, join Brigham and Women’s Hospital for the weekly Clinical Pathology Conference lecture series featuring Wyss Core Faculty member James Collins. James Collins is a founder of the field of synthetic biology and a pioneer in the application of systems biology concepts to solve major biomedical problems. His internationally acclaimed research uses network... Free and open to public
Multimedia 16
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Video/AnimationmiSherlock – Detecting COVID-19 Variants from SalivaDespite increasing vaccination rates, new, more-infectious variants of SARS-CoV-2 could prolong the COVID-19 pandemic. Researchers at the Wyss Institute at Harvard University and MIT have created a low-cost, CRISPR-based diagnostic platform that can detect SARS-CoV-2 variants in a patient’s saliva without the need for any additional equipment. The team hopes their device will enable more... -
Video/AnimationBeating Back the Coronavirus – COVID-19 detecting face maskUsing freeze-dried cell free reactions and CRISPR-based biosensors, researchers at the Wyss Institute and M.I.T. have created a face mask that can detect the SARS-CoV-2 virus in a wearer’s breath in under 90 minutes. Such a mask would allow medical professionals to quickly identify COVID-19 patients and begin effective treatments. This facemask is a proof-of-concept... -
Video/AnimationWearable Synthetic Biology – Clothing that can detect pathogens and toxinsWhat if we could create clothing that harnesses synthetic biology to detect the wearer’s exposure to toxins and pathogens? A team of researchers at the Wyss Institute and M.I.T. did just that byembedding freeze-dried, synthetic biology-based sensors into flexible materials and textiles. These sensors can detect pathogens such as the SARS-CoV-2 virus and toxins such... -
Audio/PodcastHarnessing the Power of Artificial Intelligence & Synthetic Biology To Usher In A New Age of Drug Discovery: Jim Collins3 Takeaways features intimate conversations and insights from the world’s best thinkers, business leaders, writers, politicians, scientists, and other newsmakers. Each episode ends with the 3 key takeaways the leading figure has learned over their career. It’s hosted by Lynn Thoman. James Collins, Wyss Core Faculty member and co-inventor of the technology behind Covid vaccines,... -
Video/AnimationUsing deep learning to detect cancerous skin lesionsMelanoma is a very severe cancer that is often diagnosed too late to save patients’ lives, and most people do not regularly visit a dermatologist for skin exams. Early-stage identification of suspicious pigmented lesions (SPLs), ideally by primary care providers, could lead to improved melanoma prognosis. Researchers at the Wyss Institute and MIT have developed... -
Audio/PodcastLab Notes #1 | A wearable diagnostic for COVID-19The Allen Institute is dedicated to answering some of the biggest questions in bioscience and accelerating research worldwide. They are a recognized leader in large-scale research with a commitment to openly sharing their data, tools and knowledge with scientists around the world. In the first episode of their podcast Lab Notes, they interview Wyss Core...