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Technologies 15

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• Blood Clot Dx
  An ultra-sensitive triage test that identifies patients at risk for blood clots before they happen, enabling proactive treatment to reduce complications and deaths across a wide range of conditions.
• ReConstruct: Vascularized Tissue for Breast Reconstruction and Augmentation
  ReConstruct is a platform for growing, vascularizing, and implanting patient-derived tissues that enable safer breast reconstruction after cancer surgery.
• HarborSite: Precise and Efficient Gene Editing for Next-Generation Gene Therapies
  The HarborSite next-generation gene therapy platform enables integration of therapeutic genes into genomic safe harbors using highly specific and efficient recombinases to enable more predictable, safe and durable gene therapies.
• Soft Robotic Glove for Neuromuscular Rehabilitation
  The soft robotic glove helps restore lost hand function in patients with neurological conditions using inflatable chambers that gently bend and straighten the fingers repeatedly. Wyss startup Imago Rehab launched in 2021 to commercialize this technology for at-home rehabilitation of stroke survivors, and aims to expand its offerings into other areas of rehabilitation.
• SomaCode: Getting Cell Therapies Where They Need to Go
  SomaCode is solving the problem of cell therapy delivery by identifying unique molecular “zip codes” for disease and engineering cells to home to those zip codes, making cell therapies safer and more effective.
• Athlete-Derived Probiotics
  FitBiomics is commercializing probiotic supplements based on unique combinations of microbes found in elite athletes’ guts to help optimize the health and function of all humans.

Collaborations 4

• Brigham-Wyss DxA
  The Wyss DxA's clinical partners from Brigham and Women’s Hospital identify the most pressing unmet diagnostic needs, provide access to high-quality patient samples for our Biomarker Discovery Laboratory (BDL) and Brigham-Wyss DxA collaborators, and provide invaluable feedback and guidance on the engineering and validation of cost-effective, sensitive, and specific diagnostic tests.
• Biomarker Discovery Laboratory (BDL)
  Bridging the diagnostic gap from biomarker discovery to market-ready test kits and instruments through cutting-edge technology development and clinical collaboration.
• Wyss Brain Targeting Program
  Advancing brain delivery approaches that enable more safe and effective brain-targeted therapeutics.
• i3 Center: Biomaterials to Create T Cell Immunity
  Cancer immunologists and biological engineers are developing new biomaterials-based approaches to develop new anti-cancer immunotherapies for treatment-resistant cancers.

News 141

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• Press Release
  
  Ultrasensitive test detects biomarkers for specific form of dementia
  May 5, 2026
• Press Release
  
  Wyss Institute technologies enable breakthrough in astronaut health research aboard NASA’s Artemis II mission
  April 9, 2026
• Press Release
  
  Toward autonomous self-organizing biological robots with a nervous system
  March 17, 2026

Multimedia 44

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  Audio/Podcast
  Next-Gen Toxicology: Inside the Organ Chip Revolution with Donald Ingber
  In this episode of ToxChats, hosts Lauren Walker and Sarah Benjamin sit down with the groundbreaking Donald Ingber—visionary scientist, engineer, and Founding Director of the Wyss Institute. Ingber shares how his unique path through medicine, biology, and design converged to spark breakthroughs such as human Organ Chips—systems that are redefining toxicology, drug development, and disease...

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  Video/Animation
  Reimagine the World – Volume 4 – ReConstruct Edition
  Denise Skok, a two-time breast cancer survivor, Luba Perry, a scientist at the Wyss Institute, and Samuel Lin, a plastic surgeon collaborating with the Wyss Institute, are all working to reimagine a world where breast cancer patients have better reconstruction options. The ReConstruct project at the Wyss Institute uses adipose tissue assembled from a patient’s...

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  Video/Animation
  ReConstruct – 3D Bioprinted Vascularized Fat Tissues for Breast Reconstruction
  Breast cancer affects 15% of all women. Current options for breast reconstruction are insufficient and have poor patient outcomes. A research team at the Wyss Institute is addressing this clinical need by fabricating vascularized adipose tissue flaps for therapeutic use. Credit: Wyss Institute at Harvard University

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  Video/Animation
  Bridging science, engineering, and art: from mechanobiology to Human Organs-on-Chips
  In this Marsilius Lecture, Wyss Founding Director Don Ingber shares his personal path from a serendipitous experience in an undergraduate art class that led to his discovery of how living cells are constructed using “tensegrity” architecture and how this contributed to the birth of the field of Mechanobiology to his more recent work on human...

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  Video/Animation
  Reimagine the World: Volume 1
  Four Wyss Institute scientists, Mariana Garcia-Corral, Pawan Jolly, Megan Sperry, and Mike Super, share how they would Reimagine the World and the personal stories that fuel their passion for the work they are doing. We’d love to hear how you would Reimagine the World! Please visit the following link to share your ideas: https://wyss.typeform.com/to/o9xM7cG1 Credit:...

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  Video/Animation
  SomaCode: GPS for Cell Therapy
  Just like zip codes help drivers navigate to specific addresses using a GPS system, the molecular ‘zip codes’ identified via the SomaCode platform can be used to deliver cell therapies to their specific targets in the human body, increasing the therapies’ efficacy and reducing side effects. Credit: Wyss Institute at Harvard University