Technologies search results
19 Results for ''
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Ropirio: Novel Treatments Targeting the Lymphatic System
Ropirio is commercializing the world’s first drug that directly targets and reactivates lymph vessels, a portfolio of other lymph-targeting small molecules, and a preclinical platform for discovering more. -
AminoX: Making Better Protein Drugs, Quicker and Cheaper
AminoX enables protein drugs to only become active in the tumor microenvironment and not elsewhere in the body to avoid immune-related adverse effects in the body. By designing and building non-standard amino acids into strategic positions of protein drugs, AminoX provides tumor-specific, and longer-lasting target inhibition. -
Catalytic Materials: Cheaper, Better Air Purification for a Healthier World
Our catalytic materials are inspired by the nanostructure of butterfly wings and enable affordable air purification for a variety of applications. -
eRapid: Multiplexed Electrochemical Sensors for Fast, Accurate, Portable Diagnostics
Handheld electrochemical sensors have revolutionized at-home medical testing for diabetics, but they have not yet been successfully applied to diagnosing other conditions. These sensors are based on the activity of an enzyme, and there are only a limited number of enzymes that can be used to detect biomarkers of human disease. An alternative, much more... -
DNA Nanostructures for Drug Delivery
Researchers at the Wyss Institute have developed two methods for building arbitrarily shaped nanostructures using DNA, with a focus on translating the technology towards nanofabrication and drug delivery applications. One proprietary nanofabrication technique, called “DNA-brick self-assembly,” uses short, synthetic strands of DNA that work like interlocking Lego® bricks. It capitalizes on the ability to program... -
Sugar-to-Fiber Enzyme for Healthier Food
In collaboration with Kraft Heinz, our sugar-to-fiber product can convert sugar in food products into prebiotic fiber in the human gut, reducing the amount of sugar absorbed into the bloodstream without altering the amount of sugar in existing food product recipes. -
eRNA: Enzymatic RNA synthesis for better drugs
EnPlusOne Biosciences is enabling RNA oligonucleotide manufacturing at scale, meeting the increasing demand for RNA drugs with an enzymatic process that is more efficient and creates a smaller environmental footprint. -
Sparkle: Instant Biosensors for Real-Time Imaging
Sparkle is revolutionizing the binder assay industry by harnessing novel chemistry to create instant fluorescent biosensors for a wide variety of uses. -
eRapid: Multiplexed Electrochemical Detection of Complex Diseases
StataDX licensed the eRapid portable electrochemical sensing technology to develop diagnostics for neurological, cardiovascular, and renal diseases with a first focus on building a point-of-care platform for difficult-to-detect neurological disorders. -
Nanoarchitectures for Air Purification
Metalmark is using the Wyss Institute's butterfly-inspired nanoarchitecture coating to create air purification technology that can destroy airborne pollutants including chemicals, viruses, and smog at a fraction of the cost of current catalytic converter systems. -
directEsense: Revolutionizing Animal Diagnostic Testing at the Point-of-Care
Electrochemical biosensors using a novel surface chemistry offer new opportunities for portable diagnostics with the potential to detect many disease biomarkers in animals and beyond. -
Rapid Metabolite-Sensing System for Blood Lactate
In emergency medicine, blood lactate levels are a reliable real-time indicator of the severity and mortality risk of conditions that occur as a result of poor blood circulation and oxygen supply to organs and tissues (hypoperfusion), such as in patients with sepsis, cardiac arrest, stroke, major trauma, cystic fibrosis and other conditions. Lactate levels also... -
Bone Marrow-Like Scaffolds for Accelerating Immune Reconstitution
An implantable bone marrow cryogel to accelerate the full reconstitution of the immune system, including T cell immunity, in patients that received chemotherapy and a bone marrow transplant. This could provide an off-the-shelf, material-based solution for patients with severe blood disorders whose immunity is recovering only slowly after treatment. -
Liquid-Infused Tympanostomy Tubes
Novel ear tubes coated with proprietary liquid-infused medical-grade polymers that form a frictionless, biofouling-resistant layer inside the tube, dramatically reducing the adhesion of biofluids, human cells, and common ear infection-causing bacterial strains by about 99% when compared with conventional tympanostomy tubes. -
T Cell Traps
T cells, a subtype of white blood cells, play key roles in cell-mediated immunity, be it to fight infections and cancer or, when corrupted, to react against the body’s own cells in more than 80 autoimmune diseases, including type I diabetes, multiple sclerosis, rheumatoid arthritis and others. However, isolating disease-related T cells from the body... -
Bioplastics
Humans have produced roughly 8,300 million metric tons of plastic since the 1950s, the vast majority of which has been thrown out as waste. Only about 9% of that plastic waste has been recycled and 12% has been incinerated, leaving 79% of it to accumulate on our land and oceans, harming the environment, the food... -
Liquid-Gated Membranes for Filtration
Just like pores in living organisms that control the absorption and excretion of fluids, gases and solids in response to their environments, flow-gating membranes have proved very useful for many mechanical systems, such as gas and liquid separators, dialysis machines, or open heart bypass pumps. But conventional approaches to create synthetic “gated pores” within those... -
SLIPS: Slippery Liquid-Infused Porous Surfaces
The need for an inexpensive, super-repellent surface cuts across a vast swath of societal sectors—from refrigeration and architecture, to medical devices and consumer products. Most state-of-the-art liquid repellent surfaces designed in the last decade are modeled after lotus leaves, which are extremely hydrophobic due to their rough, waxy surface and the physics of their natural... -
MAGE: Multiplex Automated Genomic Engineering
Developed at the Wyss Institute, the multiplex automated genome engineering (MAGE) technology harnesses the natural principles of evolution to do all the heavy lifting of genome design and automates these steps to dramatically shorten the time scale required to produce microbes with specialized functionalities for manufacturing, sensing and therapeutic applications. Genome engineering has a wide...