Focus Area: Living Cellular Devices
127 Results for 'Living Cellular Devices'
- Technologies (9)
- Collaborations (1)
- Team (0)
- News (93)
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Technologies 9
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Instrument-Free Molecular Diagnostics
A synthetic biology-based molecular diagnostics platform that enables the creation of low-cost, highly accurate tests for non-clinical settings. -
AminoX: Making Better Protein Drugs, Quicker and Cheaper
AminoX enables protein drugs to only become active in the tumor microenvironment and not elsewhere in the body to avoid immune-related adverse effects in the body. By designing and building non-standard amino acids into strategic positions of protein drugs, AminoX provides tumor-specific, and longer-lasting target inhibition. -
Engineered Live Biotherapeutic Product (eLBP) to Protect the Microbiome from Antibiotics
eLBP is a safe and cost-effective therapeutic for patients treated with beta-lactam antibiotics that safeguards against the loss of health-essential microbes while preventing the development and spread of antibiotic resistance. -
Paper-Based Diagnostics
With the imminent threat of new pandemics and frequent disease outbreaks exemplified by the recent Ebola and Zika epidemics, there is a growing need for low-cost, easily deployable and simple-to-use diagnostic tools. The Wyss Institute has developed paper-based synthetic gene networks as a next generation diagnostic technology for use in global healthcare crises and patient... -
Sugar-to-Fiber Enzyme for Healthier Food
In collaboration with Kraft Heinz, our sugar-to-fiber product can convert sugar in food products into prebiotic fiber in the human gut, reducing the amount of sugar absorbed into the bloodstream without altering the amount of sugar in existing food product recipes. -
Sparkle: Instant Biosensors for Real-Time Imaging
Sparkle is revolutionizing the binder assay industry by harnessing novel chemistry to create instant fluorescent biosensors for a wide variety of uses.
Collaborations 1
Kraft Heinz PartnershipNews 93
Multimedia 24
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Video/AnimationEngineering Living Materials with Peter Q. NguyenIn this episode of the CoreSpin Podcast Interview Series, host Misha Bagirov sits down with Wyss Senior Scientist Peter Q. Nguyen, Ph.D., to explore how synthetic biology can turn biofilms into useful materials, embed cell-free systems into wearables (like COVID-sensing masks), and program probiotics as future therapeutics. We also talked about the philosophy behind bioengineering,... -
Video/AnimationAminoX: Making Better Protein Drugs, Quicker and CheaperA synthetic biology and advanced chemistry platform that efficiently incorporates non-standard amino acids by hacking the ubiquitous protein synthesis process. Credit: Wyss Institute at Harvard University -
Video/AnimationPeter Nguyen: Biology Engineering, Bigfoot Hunting, and Better Climate TechnologyWyss Senior Scientist Peter Nguyen received a B.S. in Biochemistry and B.A. in Philosophy from the University of Texas, his M.Bs. from the Keck Graduate Institute, and his Ph.D. in Biochemistry from Rice University. At the Wyss Institute, Peter currently works on programmable probiotics and freeze-dried cell-free manufacturing technology across multiple platforms. His research interests... -
Video/AnimationNucleoTide – CRISPR-based biosensors for rapidly detecting harmful marine microbesThe warming of the oceans due to climate change has increased the frequency and potency of harmful algal blooms. These algae species produce toxins that can harm or even kill people, fish, shellfish, marine mammals, and birds. Researchers at the Wyss Institute are working to develop inexpensive sensors that could detect dangerous algae species earlier... -
Video/AnimationeToehold: an RNA-detecting control element for use in RNA therapeutics, diagnostics and cell therapiesThis animation shows an example of an eToehold that detects and signals the presence of a specific viral RNA in a human cell. After the virus has injected its RNA into a host cell, the RNA acts as a “trigger RNA” by binding to a complementary sequence within the eToehold specifically engineered for its detection.... -
Video/AnimationmiSherlock – Detecting COVID-19 Variants from SalivaDespite increasing vaccination rates, new, more-infectious variants of SARS-CoV-2 could prolong the COVID-19 pandemic. Researchers at the Wyss Institute at Harvard University and MIT have created a low-cost, CRISPR-based diagnostic platform that can detect SARS-CoV-2 variants in a patient’s saliva without the need for any additional equipment. The team hopes their device will enable more...